Dr. John Cush RheumNow
5 years 6 months ago
The Reflecting Rheum: Top Publications from 2020 Covering SpA and Still’s Disease
Sponsored by Novartis Medical Affairs
Listen to a panel of experts share their views on top spondyloarthritis and Still’s disease publications from 2020.
View Now: https://t.co/rxTAwQNalx https://t.co/y8wnHSmBug
Dr. John Cush RheumNow
5 years 6 months ago
Phase III RCT of apremilast showed no benefit in ankylosing spondylitis pts. 490 AS pts recv placebo or apremilast 20 mg or 30 mg bid 24 wks. The ASAS 20 was the same in all groups (PBO: 37%; 20 mg 35%; 30 mg 33). 2 yrs Xray changes were equal too. https://t.co/ILYtVMZp80
Several weeks ago, at the Rheumatology Winter Clinical Symposia, an interesting debate between Drs. Orrin Troum and Marty Bergman hashed over the concept of whether rheumatologists should sub-specialize with a practice, research or career devoted to one disease ("Super Rheum"), or be "selective" about what disorders and diseases they would treat or just be a generalist.
Palmoplantar psoriasis (PPP) is a therapeutically challenging variant of psoriasis; nonetheless, a prospective, randomized, active-controlled trial from India suggests that apremilast is effective and safe in patients with PPP.
Dr. John Cush RheumNow
5 years 6 months ago
Concise overview of Ehlers-Danlos syndrome from Medscape...FYI https://t.co/acHSoEhVVF
Dr. John Cush RheumNow
5 years 6 months ago
News Feature: Enthesitis Responses to Secukinumab in Spondylitis Patients
https://t.co/U7qfwwA2as https://t.co/lFa5LdfkIZ
Dr. John Cush RheumNow
5 years 6 months ago
Epi study of Scleritis in the UK (1997-2018) shows incidence declined from 4.23 to 2.79/100K persons/yr. Scleritis pts have 2 fold incr risk of IMIDs- esp GPA, Behçets Sjögrens, ReA, RA, SLE, Crohns, SLE & AS (OR 51 to >3). https://t.co/FzaCLRvmEX https://t.co/98M5o66fpD
Dr. John Cush RheumNow
5 years 6 months ago
Great full read NEJM review of Extrahepatic manifestations of Chronic HCV Infection; 1) mixed cryo vasculitis; 2)20-30% w/ HCV related Sicca (w/ SSA, SSB); 3) fatigue & FM; 4) AutoAbs: 70% RF+, <40% ANA+, 15% ACL Abs, 7% smooth muscle Abs https://t.co/YrIJbs8P8k
Dr. John Cush RheumNow
5 years 6 months ago
Charcot (neuropathic) arthritis: often manifests as exaggerated bony hypertrophy w/o joint pain. Common causes(sites): diabetes (TMT ankle), tabes dorsalis/syphilis (hip or knee), syringomyelia (Shoulders, elbows) . Also CPPD, steroids, alcohol, amyloid https://t.co/SrYYrVjSq3
JAMA Dermatology has published a Danish national cohort study showing that potent topical corticosteroid use was associated with an increased risk of osteoporosis and major osteoporotic fractures with a dose-response association for cumulative use.
Dr. John Cush RheumNow
5 years 6 months ago
BC Canada population study shows newly diagnosed #SLE patients (n=5,169) have a higher rate of 1st serious/sever infections (1.8-fold), and more total severe infections (2.1-fold) and infection-related mortality (1.6-fold) vs general population. https://t.co/acDk0WYSby
A multicentre, retrospective study examined MSA profiles (by immunoprecipitation) from 96 juvenile idiopathic inflammatory myopathies (JIIM) at nine pediatric rheumatology centres in Japan. MSA were found in 85 of 96 cases with over 90% of patients having one of the following three MSA types:
Dr. John Cush RheumNow
5 years 6 months ago
Rinvoq (upadacitinib) was slated for a psoriatic arthritis indication this month, but now that has been pushed back ~90days, pending further FDA review of the benefit-risk profile for upadacitinib in psoriatic arthritis https://t.co/FeBOrNIbTo
Dr. John Cush RheumNow
5 years 6 months ago
Have you listened to this week's podcast? We answer listener questions.
https://t.co/LXW8uyFGNP
Dr. John Cush RheumNow
5 years 6 months ago
News Feature: Comparison of Three Coronavirus Vaccines
https://t.co/omxsA8W3nQ https://t.co/s7dc9NwMQo

