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A study from Leeds suggests 'multi-dimensional remission' (MDR) can be seen in one-third of RA patients achieving DAS28-remission; such patients have better patient-reported outcome measures, making it an optimal goal, especially from a patient's perspective.
RCT of 139 knee OA pts given either curcumin 500-mg tid or diclofenac 50-mg bid. At days 14 and 28 both had similar improvement in pain and KOOS score

Dr. John Cush RheumNow

7 years 1 month ago

RCT of 139 knee OA pts given either curcumin 500-mg tid or diclofenac 50-mg bid. At days 14 and 28 both had similar improvement in pain and KOOS score; but curcumin had better tolerance, less GI sxs and H2 blocker use. https://t.co/tcsDQWQOMg

Retrospective review of US-guided Synovial Biopsies performed (clinical practice n=52, research n=12) - syn tissue obtained in 88%. Utility/impact was

Dr. John Cush RheumNow

7 years 1 month ago
Retrospective review of US-guided Synovial Biopsies performed (clinical practice n=52, research n=12) - syn tissue obtained in 88%. Utility/impact was good (37% Dx impact, >95% PPV or NPV for infection & research 92% success. https://t.co/A7vzIHnKH1
Study of 1272 RA pts, 69.5% were seropositive. Seropositive RA patients had two-fold increased risk for abnormalities on PFTs (ORs ranging from 2.48

Dr. John Cush RheumNow

7 years 1 month ago
Study of 1272 RA pts, 69.5% were seropositive. Seropositive RA patients had two-fold increased risk for abnormalities on PFTs (ORs ranging from 2.48 RLD, 3.12 COPD & 2.30 DLCO abnl; associations were stronger for RF+ than for CCP+. https://t.co/RQ5GgoGqwA
Thurs 8AM - start of the 2nd NIH Symposium on Autoinflammatory and immune-dysregulatory Diseases - World experts on IL-1

Dr. John Cush RheumNow

7 years 1 month ago
Thurs 8AM - start of the 2nd NIH Symposium on Autoinflammatory and immune-dysregulatory Diseases - World experts on IL-1 mediated autoinflammatory diseases, autoinflammatory Type-I interferonopathies, MAS/HLH, LIVE STREAMING AT 8AM EST https://t.co/XJ4EOIXyYm
Osteoporosis treatments were not linked with reduced overall mortality, according to a meta-analysis of placebo-controlled trial data. Looking at data from 38 clinical trials, there was no significant association found between all drug-based osteoporosis treatments and overall mortality rate (risk ratio 0.98, 95% CI 0.91-1.05), reported Steven Cummings, MD, of the San Francisco Coordinating Center, and colleagues.
Retrospective review of temporal artery biopsies from Johns Hopkins Wilmer Eye institute from 2007-17 shows the adjusted

Dr. John Cush RheumNow

7 years 1 month ago
Retrospective review of temporal artery biopsies from Johns Hopkins Wilmer Eye institute from 2007-17 shows the adjusted incidence rate of Bx+ GCA was 3.1 (1.0-5.2) in blacks and 3.6 ( 2.5-4.7) per 100 000 white patients; higher in women (1.9x vs Men) https://t.co/MeO9cBqovg
CMAJ reports on a case controlled study of >3000 pts shows GERD to be a a risk factor for TMJ disorders (OR 2.74; 1.8

Dr. John Cush RheumNow

7 years 1 month ago
CMAJ reports on a case controlled study of >3000 pts shows GERD to be a a risk factor for TMJ disorders (OR 2.74; 1.88 to 3.98) with such patients having a higher rates of somatization, anxiety and sleep disorders. https://t.co/jrTPCOVouI
Analysis of 128 Pediatric Rheum pts (JIA, FMF, etc) analzyed for reactions to 8 different biologics during 32,494 infusi

Dr. John Cush RheumNow

7 years 1 month ago

Analysis of 128 Pediatric Rheum pts (JIA, FMF, etc) analzyed for reactions to 8 different biologics during 32,494 infusions/injections - the frequency of anaphylaxis (from TCZ or RTX) was 3.9% in children. https://t.co/GzvcR0R7Bv

Telemedicine study of 122 #RA patients in the Alaska Tribal Health System shows that video telemedicine was more in pts

Dr. John Cush RheumNow

7 years 2 months ago
Telemedicine study of 122 #RA patients in the Alaska Tribal Health System shows that video telemedicine was more in pts with higher disease activity, positive views of telemedicine, and whose physicians used telemedicine more often. https://t.co/Y95ihyfSs8
A study of pregnancy outcomes in 98 women with juvenile idiopathic arthritis (JIA) who were exposed to DMARDs shows no increased risk of major adverse pregnancy outcomes.A total of 152 pregnancies in 98 women with JIA and 39 pregnancies involving 21 male patients as partners were reviewed. The majority had a polyarticular JIA (61%). The average age at first pregnancy was 24.1 years, and their mean disease duration was 13.8 years.
Dermatomyositis with anti-MDA5 Ab is at high risk of severe rapid interstitial lung disease. Study of 31 MDA-5+ pts show

Dr. John Cush RheumNow

7 years 2 months ago
Dermatomyositis with anti-MDA5 Ab is at high risk of severe rapid interstitial lung disease. Study of 31 MDA-5+ pts shows those with pneumomediastinum at higher risk for mortality, liver dysfunction, worse respiratory dz and Chest CT scores https://t.co/puFPLG2kOx
87 #Gout patients treated with ULT and followed with serial Xrays and DECT scanning shows that lowering uric acid in a T

Dr. John Cush RheumNow

7 years 2 months ago
87 #Gout patients treated with ULT and followed with serial Xrays and DECT scanning shows that lowering uric acid in a T2T strategy did not change xray over 2 years, but did show significantly less urate erosions by DECT. https://t.co/XRwkyyI4lr
Immunologic remission in rheumatoid arthritis, defined as the disappearance of anti-citrullinated protein antibodies and rheumatoid factor, was seen infrequently among patients achieving sustained clinical remission and did not correlate with the disappearance of symptoms, a long-term Dutch study found.
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