Dr. John Cush RheumNow
7 years 3 months ago
Study of 1224 SLE pts found 7% with neuropathies (PNS) w/ 2/3 attributable to SLE. 67% PNS occurred w/in 3 mos of SLE diagnosis. Periph. polyneuropathy was most common (43%). PNS pts were older, w/ higher SLEDAI-2K, Sjogrens, livedo, HTN, DM. https://t.co/G7l2GGbmgR
A small study looked at whether reducing the number of opioid tablets prescribed after knee surgery would reduce postoperative use and if preoperative opioid-use education would reduce it even more.
Minority groups in the U.S. have differing rates of Sjögren's syndrome and exhibit distinct clinical patterns of the disease, a large cross-sectional study revealed.
The percentage of American Indians in a SS cohort of 610 patients was much higher than expected, at 25.3%, whereas the percentage of African Americans was lower, at 3.1%. In addition, American Indians had higher levels of disease activity and more extraglandular manifestations,
Dr. John Cush RheumNow
7 years 3 months ago
2,899 RA and 112,571 OA pts had THA or TKA. RA had more infections (HR 1.29;1.03-1.61) post THA/TKA, but fewer VTE (HR 0.60; 0.26-0.98) post TKA. Biologics in RA had a similar infx risk but more VTE (HR 4.82;1.67-13.9) vs non-biologics. https://t.co/Lv1QLbjZjx
Dr. John Cush RheumNow
7 years 3 months ago
137 consecutive RA pts were evaluated by electronic stethoscopy of 4 lung fields to identify "VELCRO" lung sounds as an indicator of early ILD by HRCT. Sensitivity =93.2% and specificity=76.9%, Dx accuracy =83.9%. correctly classified 115/137 pts. https://t.co/0HWYLvgmTL
Dr. John Cush RheumNow
7 years 3 months ago
"Therapeutic Update: Biosimilars in Rheumatology" video series features nine experts talking about biosimilars, sponsored by Sandoz, Inc. Visit RheumNow to watch: https://t.co/1vmnEJqOSi #sponsored #biosimilars
A large study of UK family practice patients shows that polymyalgia rheumatica (PMR) or giant cell arteritis (GCA) patients treated with glucocorticoids are at an increased risk of bacterial, viral, parasitic and fungal infection, even at daily doses of less than 5 mg prednisolone.
Dr. John Cush RheumNow
7 years 3 months ago
After reviewing the safety data, the FDA has removed the risk ofosteoporosis and fracture from the drug facts listing for OTC proton pump inhibitor (PPI) medications https://t.co/RnjtTl2oVV
Patients with SLE are at increased risk for HF, not just of MI and stroke, with risk similar to that of patients with diabetes, researchers found in an analysis of Medicaid data.
Dr. John Cush RheumNow
7 years 3 months ago
Study of PsA (N = 341) pts starting secukinumab with or without a baseline loading dose of SEC 150 mg, showed equal ACR20 responses at week 16 - 41.2% vs 39.8%. Despite some w/ an earlier response, the SEC loading dose may not be necessary. https://t.co/d3z9AQoeGM
Dr. John Cush RheumNow
7 years 3 months ago
The RheumNow Podcast is up! This time its a Late Breaking Abstract Wrap-Up. Watch it here>> https://t.co/ZoVE5gSdG9 or Podcast listen on iTunes, in your car on Apple Car play or on SoundCloud here>> https://t.co/6AwVH1Zjoy
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Leonard Calabrese LCalabreseDO
7 years 3 months ago
Give me your take for my next ED in @HealioRheum on DTC-Direct to-consumer adverstising of Drugs/Biologics (as seen on national TV news : I am reasonably in favor of ( @psufka @DrBhana @AngusWorthing @RheumNow @autoimmunitymd @AutoimmuneList @SjogrensOrg )
Dr. John Cush RheumNow
7 years 3 months ago
CDC reports a 3-10mos shortage of Aplisol, a PPD product. Another PPD product, Tubersol is available for skin testing. CDC recs to use IGRA blood tests for TST & prioritize TSTs. Switching from PPD to IGRA may result in conversions requiring interpretation https://t.co/eJGOHVCbkO
Dr. John Cush RheumNow
7 years 3 months ago
"Clinicians should assess test results based on the person's likelihood of infection and risk for progression to TB disease, if infected," according to the CDC.
MMWR. 2019;68:552-553. https://t.co/eJGOHVCbkO

