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Anti-TNF mAbs, JAKi & anti-IL17 Rx appear protective against anterior Uveitis in AxSpA pts. Network Metanalysis of 4

Dr. John Cush RheumNow

2 years 9 months ago
Anti-TNF mAbs, JAKi & anti-IL17 Rx appear protective against anterior Uveitis in AxSpA pts. Network Metanalysis of 44 trials, AU IR -TNF mAb: 4.1, ETN: 5.4, IL17i: 2.8, JAKi: 1.5, & placebo: 10.8. AU risk: TNFi < JAKi < IL-17i < ETN << PBO https://t.co/3zIcvuIaBV https://t.co/UseZ6t00EB
Congratulations to Professor Paul Emery OBE on being named CBE: Commander of the Most Excellent Order of the British Emp

Dr. John Cush RheumNow

2 years 9 months ago
Congratulations to Professor Paul Emery OBE on being named CBE: Commander of the Most Excellent Order of the British Empire for his research and advances in rheumatology. He is the Versus Arthritis Professor of Rheumatology, Leeds Institute https://t.co/27igYiQxna https://t.co/KcQk5LasfN
AutoAbs in poly/dermatomyositis - ANA+ 50% to 80%, but not helpful in Dx. Look for MSA Abs - espec antisynthetase ABs (a

Dr. John Cush RheumNow

2 years 9 months ago
AutoAbs in poly/dermatomyositis - ANA+ 50% to 80%, but not helpful in Dx. Look for MSA Abs - espec antisynthetase ABs (anti-Jo-1), but also newer Abs: MDA-5, TIFF-1 gamma, NXP-2 (to be discussed #RNL24 Dr. Christopher-Stine) https://t.co/ZRlMPE48qX https://t.co/kxD1jw832C https://t.co/afC617tbmq
Sarcopenia Linked to Smoking in Osteoarthritis

Sarcopenia commonly has been linked to aging and arthritis and contribu

Dr. John Cush RheumNow

2 years 9 months ago
Sarcopenia Linked to Smoking in Osteoarthritis Sarcopenia commonly has been linked to aging and arthritis and contributes significantly to quality of life and outcomes, but the association between sarcopenia and OA has not been well established. https://t.co/anZMTGnFej https://t.co/TgVg3xpiWI
Biomarker Predicts Survival in Autoimmune Lung Disease

One major subgroup of patients with ILD arising from polymyosit

Dr. John Cush RheumNow

2 years 9 months ago
Biomarker Predicts Survival in Autoimmune Lung Disease One major subgroup of patients with ILD arising from polymyositis/dermatomyositis (PM/DM) survived significantly longer when serum levels of interferon-λ3 were relatively low, researchers found. https://t.co/PcTmzavJuC https://t.co/cNL3iTSGiF
Sarcopenia Linked to Smoking in Osteoarthritis

Sarcopenia commonly has been linked to aging and arthritis and contribu

Dr. John Cush RheumNow

2 years 9 months ago
Sarcopenia Linked to Smoking in Osteoarthritis Sarcopenia commonly has been linked to aging and arthritis and contributes significantly to quality of life and outcomes, but the association between sarcopenia and OA has not been well established. https://t.co/ucEWJjZ8Zv https://t.co/MeHw56vLjj
GNSC-001 gene therapy w/ a recombinant adeno-assoc. viral vector expressing IL-1Ra, to block IL-1. GNSC-001 now in a ph

Dr. John J Cush RheumNow

2 years 9 months ago

GNSC-001 gene therapy w/ a recombinant adeno-assoc. viral vector expressing IL-1Ra, to block IL-1. GNSC-001 now in a phase Ib, 50 pt, 10 center USA trial to assess its efficacy in Knee OA. Given as single injx in the affected joint; results in late 2024 https://t.co/jW9FHlGyC2 https://t.co/Dbv15Flqlv

Cross-sectional study of 307 RA pts, 49 (16%) used psychotropic meds and 70 (23%) had at least one fall per year. RA on

Dr. John Cush RheumNow

2 years 9 months ago
Cross-sectional study of 307 RA pts, 49 (16%) used psychotropic meds and 70 (23%) had at least one fall per year. RA on psychotropic meds had double the rate of falls (39% vs 20%). w/ an adjusted incidence rate ratio, 1.63. (p = 0.02). https://t.co/D1lhZj3he3
QD Clinic - ANA Positivity in RA
Dr. Jack Cush imparts his new New Year's Resolutions for 2024 and also reviews the news and journal reports from the past week on RheumNow.com.
New Year's Resolutions (1.5.2024)
QD Clinic - Rituximab Dosing in RA
An ultrasound study suggests that enthesitis is associated with both synovitis and tenosynovitis in patients with Psoriatic arthritis (PsA).
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