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Despite the official recognition of PMR as a distinct disease more than 60 years ago, patients with PMR are still largely treated with steroids (glucocorticoids, mostly prednisone). The persistent broad use of glucocorticoids in PMR is related to their quick initial efficacy in the majority of patients with PMR, their low price and the lack of alternative treatments and paucity of glucocorticoid-sparing treatments.
In my earlier blog, PMR: glad or bad tidings? I mentioned our PMR Voices 2021 public engagement project. This project brought home to me as a physician that although our expertise is essential, one unfortunate side-effect is that our very expertise can give us “blinkers”. One result of our “blinkers” is that we may fail to see the extent of the information gap between us and our patients with newly-diagnosed PMR. 
#PMR Polymyalgia rheumatica is very common, yet there is little research on the Dx & Management of PMR by #PCPs! May

Dr. John Cush RheumNow

2 years 11 months ago
#PMR Polymyalgia rheumatica is very common, yet there is little research on the Dx & Management of PMR by #PCPs! Mayo study prevalence 701 per 100,000 (women=870 and men =508 per 100,000 population). https://t.co/g6xIzsxjkr https://t.co/qQnouc5DPm
ACR 2022 Guideline on Glucocorticoid-Induced Osteoporosis

The ACR has published its updated recommendations for preven

Dr. John Cush RheumNow

2 years 11 months ago
ACR 2022 Guideline on Glucocorticoid-Induced Osteoporosis The ACR has published its updated recommendations for prevention and treatment of GIOP for patients receiving >3 months treatment with glucocorticoids (GCs) ≥2.5 mg daily. https://t.co/uTDBmRvCV5 https://t.co/Qx6fZSTeS5
Subcutaneous Remsima, an infliximab biosimilar, has been FDA. Celltrion has rebranded this as Zymfentra, for maintenance

Dr. John Cush RheumNow

2 years 11 months ago
Subcutaneous Remsima, an infliximab biosimilar, has been FDA. Celltrion has rebranded this as Zymfentra, for maintenance therapy in adults with moderately to severely active Ulcerative colitis and Crohn's disease following (after giving IV infliximab) https://t.co/3hb5Z7L9uw https://t.co/4gvSurl1nM
2023 EULAR Lupus Management Recommendations

EULAR has published updated recommendations for the management of systemic

Dr. John Cush RheumNow

2 years 11 months ago
2023 EULAR Lupus Management Recommendations EULAR has published updated recommendations for the management of systemic lupus erythematosus (SLE) based on new evidence and expert opinion - formulationg five overarching principles and 13 recommendations. https://t.co/9PKvsEUTM3 https://t.co/gElp6tyEQZ
JAKne? Systematic review &meta-analysis (25 studies, 10 839 pts), JAK inhibitor use was associated with an elevate

Dr. John Cush RheumNow

2 years 11 months ago
JAKne? Systematic review &meta-analysis (25 studies, 10 839 pts), JAK inhibitor use was associated with an elevated odds of acne (OR 3-5 for UPA, TOFA, BARI, Deucra; but higher for abrocitinib (OR 13.5). Seen in Derm pts but hardly at all in Rheum pts https://t.co/0XYeLLPDlK https://t.co/xN0PR1gj08
Safety Profile of a JAKi in Patients with RA With up to 6.5 Years of Exposure

Long-term JAKi safety data in patients w

Dr. John Cush RheumNow

2 years 11 months ago
Safety Profile of a JAKi in Patients with RA With up to 6.5 Years of Exposure Long-term JAKi safety data in patients with RA from 6 clinical studies is available to view in the RheumNow virtual poster hall. Sponsored by AbbVie US Medical Affairs. https://t.co/KtdQgTvw4o https://t.co/R70sj3oYPH
Genetic links for Raynauds Phen (RP): Large GWAS study of 5147 RP cases in the UK Biobank cohort shows 2 robust and stro

Dr. John Cush RheumNow

2 years 11 months ago
Genetic links for Raynauds Phen (RP): Large GWAS study of 5147 RP cases in the UK Biobank cohort shows 2 robust and strong (p < 4.8 × 10−13) novel loci A) ADRA2A (rs7090046, OR per allele: 1.26) & B) IRX1 (rs12653958, OR: 1.17) as candidate causal genes https://t.co/Jho4CKmITU https://t.co/Gstxdejpc0
RheumNow Live registration is NOW OPEN! Early bird pricing through 11/30/2023. Register today!

https://t.co/7OsdPYWukv

Dr. John Cush RheumNow

2 years 11 months ago
RheumNow Live registration is NOW OPEN! Early bird pricing through 11/30/2023. Register today! https://t.co/7OsdPYWukv https://t.co/QoCxR04bJD
When #PMR Strikes Young, It Hits Hard

In this blogpost I want to talk about “young PMR”: when people develop PMR i

Dr. John Cush RheumNow

2 years 11 months ago
When #PMR Strikes Young, It Hits Hard In this blogpost I want to talk about “young PMR”: when people develop PMR in what should be the prime of their lives. By this I mean people under 65, and even people under 50. https://t.co/jHlppnddFf https://t.co/aB81hrYyHX
Controversies in #PMR

A TNR Panel discussion on controversies in PMR: diagnosis, imaging, PCP roles, Lumping vs. Split

Dr. John Cush RheumNow

2 years 11 months ago
Controversies in #PMR A TNR Panel discussion on controversies in PMR: diagnosis, imaging, PCP roles, Lumping vs. Splitting. Featuring Drs. Sarah Mackie, Wolfgang Schmidt, and Len Calabrese. Moderated by Dr. David Liew. https://t.co/QLkypnPA2G https://t.co/y5EiLkB2yq
My colleague says, “I simply refer to physiotherapy. I don’t have time to discuss exercises, we need that time to discuss medications, side-effects, etc.” I sympathise. How do we promote activity and muscle strength among our patients?
Another infliximab biosimilar has been FDA approved, but this new version of Inflectra can be given subcutaneously for patients with inflammatory bowel disease.
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