Skip to main content
CAR-T For Rheumatoid Arthritis
The first day of EULAR 2026 in London featured the opening ceremonies, a plenary session, posters nd the first round of major oral presentations to an audience of nearly 15,000 attendees. Here are a few of my favorites from the first day.
Clinicians often come across the scenario of a patient with well-controlled spondyloarthritis where the ASDAS in the low disease activity range, CRP normalised, joints clinically quiet. However, the patient returns to the clinic still reporting significant pain. Their rheumatologist adjusts the biological, waits, returns. The pain persists.
Over 70% of patients with PsA struggle with excess weight, amplifying synovio-entheseal inflammation and blunting biologic response. The rapid uptake of GLP-1RAs in rheumatology has raised an urgent mechanistic question: are clinical gains in PsA driven purely by weight reduction, or do these agents carry intrinsic anti-inflammatory properties? EULAR 2026 offered six abstracts that together illuminate, without fully resolving, this question.
πŸ“ˆ Do SIJ lesions progress in #axSpA?

DESIR cohort (n=649, 10yrs):
Yes, slowly, but bDMARDs reduce erosion progressi

Nelly ZIADE πŸ€ Nellziade

3 months 3 weeks ago
πŸ“ˆ Do SIJ lesions progress in #axSpA? DESIR cohort (n=649, 10yrs): Yes, slowly, but bDMARDs reduce erosion progression #OP0102 #EULAR2026 @RheumNow https://t.co/Ap35q9D6B4
πŸ” Best imaging outcome for #axSpA structural change?

SPACE cohort (n=332): MRI-SIJ fat lesions most sensitive to cha

Nelly ZIADE πŸ€ Nellziade

3 months 3 weeks ago
πŸ” Best imaging outcome for #axSpA structural change? SPACE cohort (n=332): MRI-SIJ fat lesions most sensitive to change #OP0103 #EULAR2026 @RheumNow https://t.co/His1BGYmEW
πŸ–₯️ Can MRI-based synthetic CT detect spinal progression in #axSpA?

COPECARE (n=25, 1yr): sCT matches ldCT with no

Nelly ZIADE πŸ€ Nellziade

3 months 3 weeks ago
πŸ–₯️ Can MRI-based synthetic CT detect spinal progression in #axSpA? COPECARE (n=25, 1yr): sCT matches ldCT with no radiation #OP0104 #EULAR2026 @RheumNow https://t.co/pe9wSMXXZQ
πŸ” Is #axSpA overdiagnosed locally?

IMPROVE-axSpA prosp study (n=969):
Yes!

Only 54% locally confirmed centrally

#

Nelly ZIADE πŸ€ Nellziade

3 months 3 weeks ago
πŸ” Is #axSpA overdiagnosed locally? IMPROVE-axSpA prosp study (n=969): Yes! Only 54% locally confirmed centrally #OP0105 #EULAR2026 @RheumNow https://t.co/VqCPbbCHLB
πŸ”Can early TNFi beat step-up csDMARDs in pSpA?

SPARTACUS RCT (n=97) says YES
60% vs 33% remission at 24 wks

#EULAR2

Nelly ZIADE πŸ€ Nellziade

3 months 3 weeks ago
πŸ”Can early TNFi beat step-up csDMARDs in pSpA? SPARTACUS RCT (n=97) says YES 60% vs 33% remission at 24 wks #EULAR2026 @rheumnow #OP0107 https://t.co/1odtcRdTLQ
πŸ’‰ IXE+TZP beat IXE alone in obese PsA?

YES - TOGETHER-PsA RCT
33.5% vs 20.4% ACR50 at week 36 in 271 patients

OP069

Nelly ZIADE πŸ€ Nellziade

3 months 3 weeks ago
πŸ’‰ IXE+TZP beat IXE alone in obese PsA? YES - TOGETHER-PsA RCT 33.5% vs 20.4% ACR50 at week 36 in 271 patients OP069 #EULAR2026 @RheumNow @DrLauraCoates @AlexisOgdie https://t.co/orvAe38alc
πŸ₯— Does diet improve PsA?

DIPSA RCT: Mediterranean/DASH/Standard all improved DAPSA in 92pts

Weight loss drove outco

Nelly ZIADE πŸ€ Nellziade

3 months 3 weeks ago
πŸ₯— Does diet improve PsA? DIPSA RCT: Mediterranean/DASH/Standard all improved DAPSA in 92pts Weight loss drove outcomes OP070 #EULAR2026 @RheumNow https://t.co/k5y7bvDbDQ
Results of this 10yr ffup study on impact of sex on clinical outcomes & spinal xray prog in SpA:
Females ⬆️ dse

sheila RHEUMarampa

3 months 3 weeks ago
Results of this 10yr ffup study on impact of sex on clinical outcomes & spinal xray prog in SpA: Females ⬆️ dse act (asdas,basdai) ⬆️enthesitis scores, S/TJCts Males ⬆️rate of xray prog(msasss) Sex diffs exist in SpA Need for sex-specific mgt AbsOP0101 @Rheumnow #EULAR2026 https://t.co/qiNzDFh08v
#EULAR2026 OP028 In 16 patients with AID (SSc,IIM, RA, IgG4,SjD, Grave’s), CD3xBCMA BiTE, Teclistamab was effective in

Md Yuzaiful Md Yusof Yuz6Yusof

3 months 3 weeks ago
#EULAR2026 OP028 In 16 patients with AID (SSc,IIM, RA, IgG4,SjD, Grave’s), CD3xBCMA BiTE, Teclistamab was effective in 15/16. Duration of GC & DMARD-free was 11 mths. 2/16 need retreatment. All had low IgG and needed IVIG. Need long-term safety data & comparative study @RheumNow https://t.co/97MUPnXRua
The first two days of EULAR 2026 have delivered a flood of new data, late-breaking science, and clinical insights. Don't

Dr. John Cush RheumNow

3 months 3 weeks ago
The first two days of EULAR 2026 have delivered a flood of new data, late-breaking science, and clinical insights. Don't spend hours sorting through hundreds of abstracts; RheumNow will do it for you. Join Dr. Jack Cush and https://t.co/V10S4oVFsv faculty as they break down the https://t.co/eAPV6h5FAn
×