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Consensus Guideline on Drug Therapy After Osteoporotic Fractures

Silverman and a panel from the IOF Fracture Working Group reviewed the data and trials to develop guidelines for the use of osteoporosis medications after incident fractures or to treat delayed fracture healing. (Citation source http://buff.ly/1rijphu)

Key recommendations from this report include:

  • Delayed fracture healing is common and prevention should be the goal. Early identification of those at risk is important.
  • There is low risk/evidence that antiresorptives (bisphosphonates) delay fracture healing.
  • Anabolic agents such as teriparatide, which enhance osteoblastic bone formation, may have a beneficial effect on fracture healing.

The panel agreed there was no negative effect of osteoporosis medications on fracture healing, and that it is safe to start osteoporosis medications as soon as possible after both vertebral and nonvertebral fracture.

Yet, the panel agreed that after an atypical femur fracture, bisphosphonate therapy should be stopped. Treatment with an anabolic agent such as teriparatide should be considered to improve healing.

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Disclosures
The author has no conflicts of interest to disclose related to this subject