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Cardiovascular Risk in Cutaneous Lupus Erythematosus

A retrospective study of cutaneous lupus erythematosus (CLE) patients finds an increased risk of atherosclerotic cardiovascular disease (ASCVD) on par with systemic lupus patients.

An IBM MarketScan Commercial Claims data analysis from 2018 to 2020 included

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🎉 RheumNow Live 2025 is just about 2 weeks away! 🌟 Don't miss expert talks, interactive panels, networking, and the Karaoke Gong Show! Early registration extended—secure your spot now! 🗓️ Virtual & in-person options available. https://t.co/EPZJMOGgNk https://t.co/cMoOTlWKYu
Dr. John Cush @RheumNow( View Tweet )

Lung Involvement in Still's Disease

A multicentre registry observational study assessed lung involvement in a cohort of Still’s disease patients, affirming pleuritis as most common and that parenchymal lung inflammatory disease is very uncommon in both children and adults.

A total of 90 Still's patients with lung

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ACR: Congress Fails to Reform PBMs, Mitigate Medicare Cuts

ACR

The American College of Rheumatology (ACR) commended the limited extension of key Medicare telehealth coverage provisions but also expressed disappointment that Members of Congress have failed to pass measures to bring transparency to pharmacy benefit manager (PBM) practices, address flawed

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QD Clinic - CREST or More? Is this CREST or Diffuse PSS? Features Dr. Jack Cush. QD Clinics - lessons from the clinic, sponsored by RNL2025 in Dallas, TX; Feb 8 & 9, 2025 Register at https://t.co/2dcFVgu8z6 https://t.co/h7e2tcOaaF https://t.co/6AceRXb4Nq
Dr. John Cush @RheumNow( View Tweet )
QD Clinic - Treating Overlap with ILD Polyarthritis, ILD, Dermatomyositis - how to treat? Features Dr. Jack Cush. QD Clinics - lessons from the clinic, sponsored by RNL2025 in Dallas, TX; Feb 8 & 9, 2025 Register at https://t.co/2dcFVgu8z6 https://t.co/CsIpdS8hyd https://t.co/I92p5U3UTp
Dr. John Cush @RheumNow( View Tweet )

Fallen Angels (1.17.2025)

Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com; and pays homage to colleagues who passed away in 2024.

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Childhood Maltreatment and the Risk of Rheumatic Diseases

EurekAlert!

A UK retrospective matched open cohort study shows that children who suffered frmo abuse, neglect or domestic abuse carry a significantly increased risk of developing rheumatoid arthritis or psoriasis in later life.    

Researchers used Dexter software and over 16 million

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Outcomes of Multisystem Inflammatory Syndrome in Children (MIS-C)

A nationwide cohort study of patients with multisystem inflammatory syndrome in children (MIS-C), a life-threatening complication of COVID-19 infection, showed that many had severe disease during the acute phase, but most recovered quickly and had a reassuring midterm prognosis.

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🚨 RheumNow Live 2025: Redefining Rheumatology 🚨 Join top experts & innovators shaping the future of rheumatology care! 💡 Cutting-edge research, interactive sessions, expert insights, & exclusive access await. Be part of the change. Register now! 👉 https://t.co/AQbd7NC2wzhttps://t.co/AcmKxGBLvb https://t.co/QlZoAhm8h8
Dr. John Cush @RheumNow( View Tweet )

Screening for Osteoporosis to Prevent Fractures - USPSTF Recommendations

The US Preventive Services Task Force (USPSTF) has done a systematic review on osteoporosis screening to prevent fractures and put forth its recent recommendations. These recommendations pertain to adults 40 years or older with no known diagnosis of osteoporosis or history of fragility

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QD Clinic - CREST or More? Is this CREST or Diffuse PSS? Features Dr. Jack Cush. QD Clinics - lessons from the clinic, sponsored by RNL2025 in Dallas, TX; Feb 8 & 9, 2025 Register at https://t.co/2dcFVgu8z6 https://t.co/eA1GijHiYu https://t.co/3EmN9WAyIR
Dr. John Cush @RheumNow( View Tweet )

BACHELOR Trial - Baricitinib in Early Polymyalgia Rheumatica

Lancet reports a French study demonstrating the efficacy of baricitinib in patients with polymyalgia rheumatica (PMR).

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Have a rheumatology question or case for Dr. Cush? Record it here and we'll feature it on an upcoming podcast. Tell us your name and where you practice rheumatology. https://t.co/UMrunimVv6 https://t.co/yZNdnAWCy2
Dr. John Cush @RheumNow( View Tweet )

Dazukibart Effective in Adults with Dermatomyositis

Lancet reports that the use of dazukibart, a selective monoclonal antibody against interferon B (IFNβ), was clinically effective in reducing disease activity in adults with active dermatomyositis (DM).

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Eltrombopag, a Potential New Treatment for ITP

A pilot trial has shown a thrombopoietin receptor agonist, eltrombopag (Promacta), to be effective in connective tissue disease-related (CTD),  refractory immune thrombocytopenia (ITP).

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EULAR: Considerations when Transitioning from Pediatric to Adult Rheumatologic Care EULAR has established guidance on best practices for delivering patient education in physical activity and self-management of pain during transitional care in rheumatology.… https://t.co/eIqbIENFNV https://t.co/NWjiapEPvP
Dr. John Cush @RheumNow( View Tweet )

Alive in 2025 (1.10.2025)

Dr. Jack Cush brings in the new year with a review of the latest from RheumNow.com

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GLP-1 Agonists Alleviate Knee Osteoarthritis

In October, the NEJM published a randomized clinical trial demonstrating the efficacy of glucagon-like peptide-1 receptor agonists (GLP-1ra) in patients with obesity and knee osteoarthritis.

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Review of of nurse-led care (NLC) vs Rheum-led (RLC) vs Usual care in RA pts - 14 studies, 3369 pts. shows NLC proves highly effective in managing RA patients, surpassing usual care and equating to rheumatologist-led care in primary and secondary outcomes.… https://t.co/evpFTT9n22 https://t.co/n8ncKG9SFt
Dr. John Cush @RheumNow( View Tweet )

Does Colchicine Lower Gout Mortality Risk?

Data from a large UK database finds that gout patients starting urate-lowering therapy (ULT) will benefit from added colchicine prophylaxis by having fewer cardiovascular events.

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EULAR: Considerations when Transitioning from Pediatric to Adult Rheumatologic Care

EULAR has established guidance on best practices for delivering patient education in physical activity and self-management of pain during transitional care in rheumatology.

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Surveys of US IBD specialty clinic pts (n=699) used SpA screening tools ( DETAIL & IBIS-Q) finding that 27% & 40%, respectively, screened positive, mostly for axial Sxs. In screen pos pts, 31% had a prior Rheum Dx or saw a rheumatologist in the year. https://t.co/1qlAl5xVfV https://t.co/HEwdLpgx2R
Dr. John Cush @RheumNow( View Tweet )

Prevalence of Autoimmune Diseases in the United States

An epidemiologic assessment of the prevalence of autoimmune diseases in the United States (US) finds that nearly 5% of the population has an autoimmune disorder, twice as many in women compared to men.

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Anti-Zoster Drug Prevents Shingles in Lupus Patients on Anifrolumab

MedPage Today

The antiviral drug valaciclovir (Valtrex), given prophylactically, kept patients with systemic lupus erythematosus (SLE) under treatment with anifrolumab (Saphnelo) from having herpes zoster attacks, researchers said, offering a potential alternative to zoster vaccination.

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