Minimal Disease Activity Falls Short in Psoriatic Arthritis Save
A small cohort study has evaluated the utility of the minimal disease activity (MDA) criteria that has been advocated for use in psoriatic arthritis (PsA) studies and clinical trials.
Among 41 patients with MDA, 7.4% did not fulfill the tender/swollen joint count. Moreover, 49% did not fulfill the skin criteria. Of the 42 patients not fulfilling MDA, 100% did not fulfill the patient pain score, 76.5% did not fulfill the patient’s global assessment, and the Psoriasis Area and Severity Index (PASI) was abnormal 65%.
These preliminary studies suggest that fulfilling the MDA criteria in PsA may still have active joints and active skin disease.
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