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Outcomes

Uncertainty on Pre-Clinical RA – Rheumatologist Survey Results

Sep 27, 2023

In June 2023, RheumNow surveyed US and non-US rheumatologists (Rheums) about how they consider and manage pre-clinical rheumatoid arthritis (RA) in their practice. 



In the last few years there have been numerous well designed and appropriately powered randomized clinical trials of pre

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Microvascular CV Disease with Severe Psoriasis

Sep 26, 2023

While comorbidities, including an increased cardiovascular (CV) risk, are associated with severe psoriasis, less is known about subclinical CV disease and when it occurs in patients with psoriasis. 



Coronary microvascular dysfunction (CMD) has been shown to be predictive of future

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Advice on Multi-Drug Failures in RA

Sep 25, 2023

What’s your next best approach to the rheumatoid arthritis (RA) patient who has failed several DMARDs and biologics?  In such cases you have to either reconsider the diagnosis (especially if seronegative) or reach into your bag of tricks.  



As many of us struggle with multi-drug

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RheumNow Podcast with Special Guest Dr. Michael Weinblatt (9.22.2023)

Sep 22, 2023

Dr. Jack Cush is joined by Dr. Michael Weinblatt as they discuss this weeks news and journal reports, including difficult RA, HLA typing and abatacept responses and new regulatory decisions. 




  1. UCB has issued a press update on its pending application for the approval of their

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Cognitive-behavioral Therapy Lessens Fibromyalgia Pain

EurekAlert!
Sep 22, 2023

In a recent randomized clinical trial of patients with fibromyalgia, cognitive-behavioral therapy (CBT)—which uses structured techniques to alter distorted thoughts and negative moods—was superior to a matched education treatment in reducing the interfering effects of pain and other aspects

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RA Associated Cancer Risk

Sep 19, 2023

A large cohort analysis of insured rheumatoid arthritis (RA) patients reveals that RA patients have a 1.69 to 2.08 fold higher risk of developing cancer, especially lymphoma or lung cancer, within 1 year of RA diagnosis.  



The analysis included nationwide health insurance claims data

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Machine Learning May Diagnose Psoriatic Arthritis Earlier

Sep 18, 2023

A machine learning approach was applied to two different population cohorts and was shown to be effective at the early identification of undiagnosed psoriatic arthritis (PsA).



It is estimated that PsA affects approximately 0.27% of the adult population, and 20% of those with with

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RheumNow Podcast – with Special Guest Dr. Peter Nash (9.15.2023)

Sep 15, 2023

This week, Dr. Jack Cush reviews the news with special guest, Dr. Peter Nash. They discuss COVID Autoantibodies, SpA life expectancy, HCQ, extraarticular RA and our approach to Early RA referrals and pre-clinical RA.

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TNR: Early RA - Referrals and Treatment

Sep 13, 2023

This Tuesday Night Rheumatology was an hour long panel discussion featuring Drs. Jack Cush, Vivian Bykerk, Glen Hazelwood and Martin J. Bergman.

The​ Panel discussed Rheumatologists ​views on Early RA referral and intake, initial treatment preferences and views on diagnosing and treating pre-

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RA Extra-articular Manifestations Declining

Sep 12, 2023

A Mayo Clinic population based cohort study shows the extraarticular manifestations of rheumatoid arthritis (ExRA) have declined with time; but the increased mortality risk of RA remains unchanged.



They defined their cohort as adult patients with incident RA (ACR Criteria positive)

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Hydroxychloroquine Adherence Lowers Cardiovascular Risks

Sep 11, 2023

Daily hydroxychloroquine (HCQ) is better than an apple a day; as a new study shows that adherence to the antimalarial agent significantly lowers future risk of cardiovascular events in rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) patients.

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RheumNow Podcast – with Special Guest Dr. Janet Pope (9.8.2023)

Sep 08, 2023

This week, Dr. Jack Cush reviews the news with special guest, Dr. Janet Pope. They discuss "Not-non-Inferior", large scale genetic screening, Zoster risk w/ newer lupus drugs, tapering, RA referral problems and the TNR webinar session on "ORAL Surveillance Revisited".

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Woeful Rheumatology Referrals

Sep 07, 2023

Early diagnosis of inflammatory arthritis (IA) is rooted in patient (self or MD) referrals. A recent analysis shows only a minority of rheumatology referrals had inflammatory arthritis, with only 21% were seen within the first 6 weeks of symptoms. 



A total of 1023 were patients

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Oral Surveillance Changes in Advanced Therapy Use in RA

Sep 06, 2023

The safety of tofacitinib and TNF inhibitors was studied in high risk rheumatoid arthritis (RA) patients in the ORAL Surveillance study, which culminated in an FDA warning in January 2021 on the cardiovascular, cancer and VTE risks associated with JAK inhibitor use. These safety concerns and

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Aortic Stenosis Risk in RA

Sep 05, 2023

A large cohort study has shown that rheumatoid arthritis (RA) patients are at an increased risk of developing aortic stenosis (AS), undergoing aortic valve intervention, or AS-related death.



The risk of incident AS, aortic valve intervention, AS-related death, and risk factors for AS

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ICYMI: ACR Guidelines for Interstitial Lung Disease in Patients with Rheumatic Conditions

ACR
Sep 04, 2023

The American College of Rheumatology released summaries of two new guidelines for the Screening and Monitoring of Interstitial Lung Disease in People with Systemic Autoimmune Rheumatic Disease and for the Treatment of Interstitial Lung Disease in People with Systemic Autoimmune Rheumatic

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Hard Decisions in RA (9.1.2023)

Sep 01, 2023

Dr. Jack Cush reviews the news and journal reports from this past week on RheumNow, and introduces our September campaign - "Hard Decisions in RA".

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SGLT2 Inhibitors as Gout Treatment

MedPage Today
Aug 30, 2023

Patients with gout and type 2 diabetes treated with SGLT2 inhibitors not only had reduced numbers of gout flares, but also lived longer compared with other such patients receiving other medications, researchers said.

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Gut Microbiome Differences Antedate JIA Development

Aug 28, 2023

Researchers have shown that gut microbiome differences may be associated with later development of juvenile idiopathic arthritis (JIA), and that such differences are present years before the disease is diagnosed.

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Hip Replacement Surgery After Age 90

EurekAlert!
Aug 28, 2023

Potentially modifiable comorbid conditions and complications have a major impact on the risks of total hip arthroplasty (THA) for people in their nineties, reports a study in The Journal of Bone & Joint Surgery.

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Biologic Adherence and Drug Survival in RA Patients

Aug 24, 2023

A real-world rheumatoid arthritis (RA) cohort study from Israel shows significant variability of drug survival using biologic disease-modifying anti-rheumatics drugs (bDMARDs) and targeted synthetic DMARDs (tsDMARDs).



A total of 753 RA patients were drawn from in a large Israeli

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ACR Guidelines for Interstitial Lung Disease in Patients with Rheumatic Conditions

ACR
Aug 24, 2023

The American College of Rheumatology released summaries of two new guidelines for the Screening and Monitoring of Interstitial Lung Disease in People with Systemic Autoimmune Rheumatic Disease and for the Treatment of Interstitial Lung Disease in People with Systemic Autoimmune Rheumatic

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WSJ: Do Younger or Older Doctors Get Better Results?

Aug 23, 2023

A recent Wall St. Journal essay (by AB Jena and C Worsham) suggests that a physician’s effectiveness has less to do with age than with how many patients they see and how well they stay up to date on research.



If admitted to the hospital would you rather your physician be in their 50s

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2023 EULAR Recommendations for Imaging in Large Vessel Vasculitis

Aug 23, 2023

EULAR has published its expert consensus regarding the recommendations for imaging in the most common types of large vessel vasculitis (LVV) -- giant cell arteritis (GCA) and Takayasu arteritis (TAK). Imaging facilitates diagnosis and rapid management to prevent vascular damage and ischemic

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Fracture Risk Quantified for Older Spondyloarthritis Patients

MedPage Today
Aug 22, 2023

Medicare beneficiaries with ankylosing spondylitis (AS) incur frequent bone fractures, a new study indicated, with the risk boosted by some unsurprising factors but also including one that was not expected.



Fee-for-service Medicare claims data from 2016-2018 showed that AS patients

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