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Tried-and-True or Something New?

Isn't it interesting that thiazide diuretics invented in 1958 are still the mainstays of hypertension therapy today?

Biosimilars and the FDA

Biosimilars are in the news and will be prominently on parade at next week's ACR meeting in San Francisco. Biosimilars are similar to, but not the same as, innovator biologics.

New Drugs, New Hope for Pulmonary Fibrosis

The Wall Street Journal reports that new drug development offers hope for people with idiopathic pulmonary fibrosis, a rare, progressive fibrosing lung disorder that affects nearly 200,000 Americans, mostly middle-aged and older adults. 

A Winning Season*

Fall is ahead and football season is here. This season only brings out my most competitive side. Winning is everything – in football and in medicine. To fail is objectionable, even cry-worthy, but it may also be motivating and humbling.

Advances in Uveitis Associated with Juvenile Arthritis

Uveitis is a common association of juvenile idiopathic arthritis (JIA) that has previously been characterized by poor visual prognosis with limited options for effective treatment.

Priorities for NIAMS Research Funding

Dr. Steven Katz describes how NIAMS sets priorities for investing congressionally-appropriated funds.

Alemtuzumab Effective in Behcet's Syndrome

Behcet's disease is difficult to treat and often has an over-reliance on corticosteroid use.  Alemtuzumab (previously known as Campath-1H) has been studed in patients with Behcet's.

Hypothyroidism is Increased in Rheumatoid Arthritis Patients

In a study that compared seropositive (RF+, CCP+) and seronegative RA with healthy participants, the frequency of thyroid antibodies was assessed.

Rituximab Induced Neutropenia

In reviewing submitted abstracts for the 2014 ACR meeting, I was surprised by several abstracts focusing on neutropenia in patients receiving rituximab.

Bidirectional Association Between Uveitis and Psoriatic Disease

A Danish population, claims-based study studied the the associations between 74,129 patients with incident psoriasis and 13,114 with incident uveitis between 1997 and 2011.

How do you handle questions about sex?

I had just finished going over the prognosis and treatment plan with my newly diagnosed rheumatoid arthritis patient. I asked if she had any questions for me.

2015 Guidelines for Idiopathic Pulmonary Fibrosis

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrosing form of interstitial pneumonia, with poor survival rates of nearly 50% at 3 years.

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