Weight Loss Improves Psoriasis

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Jennsen et al previously reported their findings regarding weight reductions ability to improve cutaneous psoriasis at the European Academy of Dermatology and Venereology (EADV) meeting in 2015, Now their results are published in The American Journal of Clinical Nutrition.

The RheumNow Week in Review – 6 January 2017

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Dr. Jack Cush reviews highlights from the first week of 2017 on RheumNow.com.

Happy New Year!

Pregnancy Outcomes in Psoriatic Arthritis

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Disease Activity Pre-pregnancy During Pregnancy Post-pregnancy Mild 10 6 4 Moderate 2 6 8 Severe 2 2 2

Biopsy Proven Renal Involvement in Sjogren's Syndrome

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A French multicenter study of primary Sjogren's syndrome (pSS) patients fulfilling the American–European Consensus Group criteria or enlarged American–European Consensus Group criteria were retrospectively studied based on having biopsy-proven renal involvement.

DMARDs Under Study for Secondary Prevention of Cardiovascular Events

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Several important lines of population and large cohort research have shown that rheumatoid arthritis (RA) patients have a substantially higher risk for myocardial infarction and major cardiovascular events.

Modest Benefits with Intraarticular Corticosteroids in Knee Osteoarthritis

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The current online edition of JAMA examines the evidence from 27 clinical trials and 1767 patients to assess the impact of intra-articular corticosteroids in patients with knee osteoarthritis (OA).

PPI Safety Issues

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There are more than 11 million proton pump inhibitor (PPI) prescriptions written each year in the United States. While these agents have dramatically changed the management and outcome of upper gastrointestinal (GI) erosive and inflammatory disorders, their use has not been without safety concerns.

Cautious Optimism for Biosimilars in Rheumatology

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A Low Risk of Inflammatory Bowel Disease with IL-17 Inhibition

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Colitis onset or worsening inflammatory bowel disease has been reported with either of the new IL-17 inhibitors, ixekizumab (IXE) and secukinumab (SEC). Large database studies show these to be rare.

CHMP Recommend Baricitinib for Approval in Europe

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Eli Lilly and Company announced last friday that the European Medicines Agency's (EMA) Committee for Medicinal Products for Human Use (CHMP) has issued a positive opinion, recommending the approval of baricitinib for the treatment of adults with moderate to severely active rheumatoid arthritis (R

A Link Between Periodontal Disease and Rheumatoid Arthritis

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Research from Johns Hopkins reports that rheumatoid arthritis (RA) patients with periodontitis exhibited patterns of autoantigen hypercitrullination similar to that seen in RA. Results published in Science Translational Medicine showed that Aggregatibacter actinomycetemcomitans can produce hypercitrullination of patient neutrophils, indicating its possible role in triggering RA. (Citation source: http://buff.ly/2hZTBG8)

BEST-D Trial: Higher Doses of Vitamin D may be Required for Optimal Osteoporosis Prevention

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Osteoporosis is a major public health problems and is associated with a high burden of fractures and subsequent increased mortality.

Risk of GI Perforations on Biologics

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Gastrointestinal perforation is a rare but serious complication that RA patients may be at particular risk for.

Osteoporosis 2016 Year in Review - No new drug approvals, and a crisis in care

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No new osteoporosis drugs hit the market this year, but two are progressing through the development pipeline and are showing promise.

Female Physicians are Better in Death, Hospital Readmission Stats

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Do hospitalized Medicare beneficiaries treated by female internists have lower rates of 30-day mortality and hospital readmission than those patients treated by men? A new study published online by JAMA Internal Medicine suggests that they do.