At EULAR 2015, Brouwer and colleagues reported on their cohort of 162 evaluable pregnancies in 239 Dutch women enrolled during 2002-2010 in the nationwide Pregnancy-Induced Amelioration of Rheumatoid Arthritis (PARA) study – a large prospective cohort of pregnant RA patients.
According to the CDC, between 4300 and 9700 children under the age of 16 are diagnosed with juvenile idiopathic arthritis each year - the cause of which is unknown.
Behcet's disease is difficult to manage, especially if the goal is to avoid corticosteroids.
Gout is the most common inflammatory arthritis affecting adults and, probably, one of the most underestimated.
Several studies have suggested that lithium chloride exhibits significant chondroprotective effects on cartilage degradation (in animal models) in response to inflammatory cytokines.
It is estimated that Lyme disease affects nearly 30,000 per year in the USA. While it is is still a disorder of the Northeast and upper Midwest, there are more areas also considered to be high risk.
The British Medical Journal reports that the combined use of NSAIDs and anti-depressants were associate with higher rates of intracranial bleeding within 30 days of initiation (Citation source http://buff.ly/1gF3uEJ).
FDA Scours the Internet for Safety Signals. A Bloomberg News report shows how the FDA is using Google or Yahoo keyword searches to identify new safety signals or drug interactions, often more than a year before they were brought to light by the FDA based on prior methodologies de
The Journal of Clinical Investigation has written a tribute noting the sad passing of Dr. Norman Talal on April 24, 2015.
Dr. Talal was an eminent researcher and clinician known for his research and education on Sjogren’s syndrome.
A systematic review of treatments used in autoimmune chronic uveitis after failure of DMARDs and at least one TNF inhibitor identified few patients (12 children and 34 adults), and few trials examining rituximab (3), abatacept (3), tocilizumab (3), and 1 each with alemtuzumab and anakin
The MedWatch June 2015 safety labeling changes were published yesterday, and updated the warnings for Xeljanz (tofacitinib). "The risk of herpes zoster is increased in patients treated with Xeljanz and appears to be higher in patients treated with Xeljanz in Japan."
Committees at academic institutions that make decisions on research and clinical trials may be conflicted, as nearly one-third of IRB members have some ties to the pharmaceutical industry.
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