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Congratulations to Dr. Georg Schett (University of Erlangen) upon receiving the 2023 Gottfried Wilhelm Leibniz Prize - h

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Dr. John Cush
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Congratulations to Dr. Georg Schett (University of Erlangen) upon receiving the 2023 Gottfried Wilhelm Leibniz Prize - highest honor from the DFG, German Research Foundation. Dr. Schett is famed for research on inflammation, autoimmunity & osteoimmunology https://t.co/Wq0EvhtvLW https://t.co/AWwCVCt4cm

A Pilot Trial of Anifrolumab in Discoid Lupus

A research report in JAMA Dermatology describes the use of the type 1 interferon receptor inhibitor anifrolumab in patients with chronic discoid lupus erythematosus (DLE). 
Itaconate - A Potential New Immunosuppressive

Researchers have revealed the modulatory effect of the anti-inflammatory metabolite itaconate (ITA) on T helper and T regulatory cells, which may lead to new therapeutic approaches to treating some autoimmune diseases.

Lancet metanalysis shows pts infected w/ SARS-CoV2 are conferred very high degree of re-infx from pre-omicron variants,

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Dr. John Cush
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Lancet metanalysis shows pts infected w/ SARS-CoV2 are conferred very high degree of re-infx from pre-omicron variants, even after 40 weeks. Protection was lower for omicron BA.1 & declined over time. Protection from severe Dz was high for all variants. https://t.co/RNgYVWQfNo https://t.co/J8U37NYXPP

Carpal Tunnel - Steroid injection vs. Night Splinting A randomized trial conducted by the UK National Health Service,

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Dr. John Cush
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Carpal Tunnel - Steroid injection vs. Night Splinting A randomized trial conducted by the UK National Health Service, studied interventions in patients with CTS and found no advantage to either CTS CSIor NS as the initial treatment of CTS. https://t.co/05AADf55uB https://t.co/m07xxffSfv

Ccancer detection study in idiopathic inflammatory myositis: found w/in 3 yrs of onset 9/1011 (0.9%) CT chest & 12/6

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Dr. John Cush
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Ccancer detection study in idiopathic inflammatory myositis: found w/in 3 yrs of onset 9/1011 (0.9%) CT chest & 12/657(1.8%) CT Dx cancer. Yield best w/ DM, TIF1γ pos. Yield very low age<40 yrs; high false(+) w/ antisynthetase synd & necrotizing myositis https://t.co/FCBwEYW1eT https://t.co/DAEj83xmam

Marathon Running Not a Risk Factor for Arthritis Intensity of distance running had no bearing on the prevalence of hip

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Dr. John Cush
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Marathon Running Not a Risk Factor for Arthritis Intensity of distance running had no bearing on the prevalence of hip and knee osteoarthritis among participants in recent editions of the Chicago Marathon, researchers reported here. https://t.co/GjgyncTGa6 https://t.co/cwIADHfNdv

29 pts w/PsA Sine Psoriasis: 16F/13M, mean age 45 yrs w/ PsA ~6.2 yrs. 54% had 1st-degree relatives with PsA. 66% had D

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Dr. John Cush
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29 pts w/PsA Sine Psoriasis: 16F/13M, mean age 45 yrs w/ PsA ~6.2 yrs. 54% had 1st-degree relatives with PsA. 66% had DIP arthritis, 39% polyarticular, 36% oligoarticular, 25% were axial. Nail findings seen in 89%, enthesitis 59%, dactylitis 62% https://t.co/FPAqosYr9C https://t.co/xr692rSZZ1

Retrospective insurance claims study of PMR &amp; GCA pts. No cases PJP (pneumocystis) found in 547 Pt-Yrs F/U in 1168 G

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Dr. John Cush
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Retrospective insurance claims study of PMR & GCA pts. No cases PJP (pneumocystis) found in 547 Pt-Yrs F/U in 1168 GCA pts and 1 case found during 7,446 Pt-Yrs F/U in 15,575 PMR pts (incident 0.07 cases per 1,000 Pt-YRs). NO NEED FOR PJP prophylaxis! https://t.co/UFlKtm88Dj https://t.co/tFYusx0O4t
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