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Drug Safety Differences w/ New Therapies in RA Safety outcomes for targeted synthetic or b/ts DMARDs used to treat RA

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Dr. John Cush
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Drug Safety Differences w/ New Therapies in RA Safety outcomes for targeted synthetic or b/ts DMARDs used to treat RA were studied using data from the ARTIS registry. https://t.co/U96LiasMhW https://t.co/f2oCHs04Q3

Case reports of anifrolumab use in 2 pts w/ chronic, scarring discoid lupus unresponsive to steriods, HCQ, immunosuppres

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Dr. John Cush
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Case reports of anifrolumab use in 2 pts w/ chronic, scarring discoid lupus unresponsive to steriods, HCQ, immunosuppressants & CTX. Case 1 SLEDAI from 13 to 2 in 24 weeks & CLASI-A from 26 to 3 in 20wks. Cs 2 CLASI-A decr 24 to 5 after 1 infusion https://t.co/JE3PVyskm4

Older Lupus Patients Need Follow-Up After Hospital Discharge Medicare beneficiaries 65 and older with lupus faced dram

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Dr. John Cush
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Older Lupus Patients Need Follow-Up After Hospital Discharge Medicare beneficiaries 65 and older with lupus faced dramatically higher mortality when they received no follow-up care during the month after a hospital stay, researchers found. https://t.co/4mFctXGQH9 https://t.co/2Q1z03myud
Gingival Inflammation Parallels Saliva “Cytokine Score”

Researchers at NYU College of Dentistry have developed a single score to describe the level of cytokines in the saliva, and this score is linked with the severity of clinical gum inflammation, according to a study published in the journal PLOS ONE. 

New Laboratory Insights for the ANA+ Consult

A new study suggests that use of ELISA assays for CXCL-10 and IFN-α can predict which ANA+ individuals may progress to developing a systemic autoimmune rheumatic disease (SARD).

Assays for cytokines (serum IFN-α or selected IFN-induced cytokines) were performed by nanoString, ELISA or Simoa. Patients were followed for 2 years for the diagnosis of a new onset SARD. 

Study of 232 pediatric #SLE pts. Over 12 mos 47% achieved LLDAS & Damage seen in 40% after 6.2 yrs F/U. Getting t

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Dr. John Cush
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Study of 232 pediatric #SLE pts. Over 12 mos 47% achieved LLDAS & Damage seen in 40% after 6.2 yrs F/U. Getting to LLDAS w/in 12 mos is assoc w less damage. LLDAS w/in 12 mos more likely in Absence of renal involvement. https://t.co/pGethJCw4e https://t.co/eYpVueIKbf
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