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Subanalysis of Scleroderma Lung Study II (MMP vs CTX in SSc-ILD) showed pt reported GI reflux (~moderate) was independen

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Dr. John Cush
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Subanalysis of Scleroderma Lung Study II (MMP vs CTX in SSc-ILD) showed pt reported GI reflux (~moderate) was independently associated with the change ILD and fibrosis over two years (but not so for esophageal dilation) https://t.co/5Gz2vfOock https://t.co/N2FsvNe24M

AS, but not PsA, has Increased Mortality Risk A recent meta-analysis showed a significantly increased risk of overall

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Dr. John Cush
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AS, but not PsA, has Increased Mortality Risk A recent meta-analysis showed a significantly increased risk of overall mortality in ankylosing spondylitis (AS) but not psoriatic arthritis (PsA), largely associated with cardiovascular-specific mortality. https://t.co/bi3q7LW4S6 https://t.co/DUc9sB4MI0

Simon Says “Don’t Do This” Dr. Jack Cush reviews this week’s journal articles, focuses on studies that should

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Dr. John Cush
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Simon Says “Don’t Do This” Dr. Jack Cush reviews this week’s journal articles, focuses on studies that should not have been done and responds to viewer questions in Ask Cush Anything. https://t.co/ZisyCRxV6L https://t.co/inYDkKKJO3

CDC: Nursing home residents not up to date w/COVID-19 vaccines have 30%–50% higher risk for COVID infx vs those up to

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Dr. John Cush
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CDC: Nursing home residents not up to date w/COVID-19 vaccines have 30%–50% higher risk for COVID infx vs those up to date. Betw 2022-23 Those vax had COVID rate of 7.2-15.6/1000pts vs 9.5-18.8/1000 pt in those unvaccinated. https://t.co/Eem2H5AMoN https://t.co/o2ZyPVswZp

VEXAS may be more common than expected A great study of a recently described rheumatologic/hematologic disorder VEXAS

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Dr. John Cush
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VEXAS may be more common than expected A great study of a recently described rheumatologic/hematologic disorder VEXAS syndrome recently appeared in JAMA, describing the frequency and presentations of UBA1 variant. https://t.co/OFaeH62eHy https://t.co/7znps74Llv
Pathogenic Impact of microRNA Cotargeting in Lupus

A group of researchers from the Graduate School of Medicine at Nagoya University in Japan have discovered the impact of microRNA (miRNA) on inflammation in lupus in mice. They identified two miRNAs that are downregulated in the disease and an uncommon situation that occurs in which multiple miRNAs regulate the same set of genes.  

Blood Test Identifies Osteoarthritis Progression A new blood test that can identify progression of osteoarthritis in t

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Dr. John Cush
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Blood Test Identifies Osteoarthritis Progression A new blood test that can identify progression of osteoarthritis in the knee is more accurate than current methods, providing an important tool to advance research and speed discovery of new therapies. https://t.co/hOAjxJhnJG https://t.co/Ehr5imPNQ4

A Shortage of Trust I’ve oft heard the truism that “Trust is in short supply”. This is so true. Those I value m

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Dr. John Cush
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A Shortage of Trust I’ve oft heard the truism that “Trust is in short supply”. This is so true. Those I value most, are the ones I trust the most. My nurse practitioner, my front desk gal, my medical partner, and my best friend... https://t.co/AXIDAJQUta https://t.co/GJwQq04dUC
Simon Says “Don’t Do This” (1.27.2022)

Dr. Jack Cush reviews this week’s journal articles, focuses on studies that should not have been done and responds to viewer questions in Ask Cush Anything.

  1. "Dry Synovitis" exist in juvenile arthritis pts? Study of 12 DS pts, says its different from Poly #JIA; onset 6.1 yrs, w/ polyarthritis, no palpable swelling, progressive LOM/contractures, neg ESR/CRP/RF/CCP, +MRI synovitis w/ osteochondral involvement. https://t.co/tL2G7QKBL4

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