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So we used to get taught about bimodal age distribution of RA onset - young people and old people. Actually, it’s ear

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David Liew
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So we used to get taught about bimodal age distribution of RA onset - young people and old people. Actually, it’s early middle age where RA diagnoses have now grown globally over 30y - right in peak productivity Global Burden of Disease data #EULAR2025 OP0240-HPR @RheumNow https://t.co/8yyrex00yy

Prédiction of PsA from PsO. Stockholm cohort, n=672): •PsA incidence 21.1/1000 PY. •AUC 0.80 for both referral and

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Antoni Chan MD (Prof)
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Prédiction of PsA from PsO. Stockholm cohort, n=672): •PsA incidence 21.1/1000 PY. •AUC 0.80 for both referral and prognostic models. •Predictors: HLA-B27, uveitis, enthesial pain, TJC, hsCRP, BMI, SAA, GlycA. •Early identification feasible. Abstract OP0178 @RheumNow https://t.co/dxdChN6VZy

Do the sites of clinical onset of PsA (i.e., swelling) correspond to those that, at the time of enrollment in the study

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Antoni Chan MD (Prof)
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Do the sites of clinical onset of PsA (i.e., swelling) correspond to those that, at the time of enrollment in the study, showed evidence of joint tenderness and/or ultrasound-detected alterations compatible with inflammation? Of 28 incident PsA cases, 68% had prior subclinical https://t.co/rAZJU6Va5x

Even after having things laid out in a great debate, rheumatologists remain unconvinced by medical cannabis #EULAR2025 @

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David Liew
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Even after having things laid out in a great debate, rheumatologists remain unconvinced by medical cannabis #EULAR2025 @RheumNow https://t.co/xMTvngS5N1

Study on the HLAs associated with the occurrence and course of acute/tender dactylitis in PsA patients. Acute dactylit

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Antoni Chan MD (Prof)
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Study on the HLAs associated with the occurrence and course of acute/tender dactylitis in PsA patients. Acute dactylitis genetics: •HLA-B27 (OR 1.71), HLA-C12 (OR 1.43), B38/C12 & B27/C02 haplotypes. •Resolution faster on b/tsDMARDs (HR 1.67); unaffected by HLA. Abstract

cool stuff at #EULAR2025 RESET #RCT - #vagal #nerve #stimulation #VNS vs sham in #RA w 1or >1 #bDMARD-IR N=242 D/C

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Janet Pope
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cool stuff at #EULAR2025 RESET #RCT - #vagal #nerve #stimulation #VNS vs sham in #RA w 1or >1 #bDMARD-IR N=242 D/C bDMARD, on #csDMARD #RA 12 yrs, 10SJC 12TJC 2.6 b/tsDMARD failure Wk12 EULAR good/mod response 61v 42% Sham▶️goes VNS ✅data= @RheumNow @eular_org abst#OP190

Intraarticular IL-1Ra Gene Therapy in Knee Osteoarthritis In a dose-escalation trial in nine participants, they observ

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Dr. John Cush
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Intraarticular IL-1Ra Gene Therapy in Knee Osteoarthritis In a dose-escalation trial in nine participants, they observed that a single intra-articular injection of the gene product led to an increase in IL-1Ra in the synovial fluid that remained elevated for up to a year. There https://t.co/qi0qHPd06j
Putting IL17i into ‘focus’ for SpA-associated uveitis
The longest studied drug for uveitis in SpA has been monocolonal TNFi Abs. Reductions of acute anterior uveitis have been found with etanercept but less impressively than adalimumab, infliximab, and in my opinion less than golimumab and certolizumab pegol. Other data have emerged for JAKi and IL17i, with respect to acute anterior uveitis.
Clinical and Therapeutic Challenges in Connective Tissue Disease and ILD
Connective tissue diseases (CTDs) and interstitial lung disease (ILD) represent a challenging intersection of systemic autoimmunity and progressive respiratory impairment. Research presented at EULAR 2025 continues to highlight the importance of CTD-ILD and the evolving landscape of therapeutic options for patients with autoimmune ILDs.

#polyrefractory #RA = failed all classes in #rheumatoid #arthritis +inflammatory #arthritis Longer disease duration Lat

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Janet Pope
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#polyrefractory #RA = failed all classes in #rheumatoid #arthritis +inflammatory #arthritis Longer disease duration Late RA Rx +power Doppler in POCUS ⬆️no refractory BMI Fibromyalgia - pain ⬇️SJC, less DAS , rapid X-ray progression #EULAR2025 @RheumNow #D2T #RA https://t.co/1sPwf3Qa3m
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