5 May 2025

Glucocorticoids in SLE: how to start, how to follow, how to stop

Current guidelines recommend limiting the use of glucocorticoids by coining the new concept of “bridging therapy”, that is, use GCs when the disease is active and get rid of them as soon as you can. This way of thinking is conceptually attractive, however, the formula for translation to real life settings is not included.

DANBIO registry study of 720 RA pts w/ a prior solid cancer (breast, colon. lung, endometrial, melanoma, bladder) in rem

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RheumNow

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DANBIO registry study of 720 RA pts w/ a prior solid cancer (breast, colon. lung, endometrial, melanoma, bladder) in remission who received any biologic DMARD, TNFi or RTX found no incr risk of CA recurrence w/ any bDMARD, TNFi, RTX. Specifically, no incr in breast CA recurrence https://t.co/YJw8qXz1yM

45 southern African American SLE pts compared to multiethnic cSLE, AA pts had signif higher Dz activity & greater da

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RheumNow

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45 southern African American SLE pts compared to multiethnic cSLE, AA pts had signif higher Dz activity & greater damage accrual. Their mean SLICC score was 8.4, SLEDAI 13, but was 7.4 @6 mos & 4,7 @1 yr. They traveled an avg distance 75 miles to see Rheum https://t.co/R8WimzY0Az https://t.co/1lOJpjO2SY

Links

Characterizing lupus in African American children in Southern United States - P… https://buff.ly/u4yGFaB

Rheumatologist Survey: What do you rely on to diagnose neuropsychiatric lupus (cerebritis)?

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RheumNow

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Rheumatologist Survey: What do you rely on to diagnose neuropsychiatric lupus (cerebritis)?

2023 report from US NHANES study says #Gout affects 12.1 million in the USA. Gout prevalence incr from 3.6% in 2011/12 t

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RheumNow

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2023 report from US NHANES study says #Gout affects 12.1 million in the USA. Gout prevalence incr from 3.6% in 2011/12 to 5.1% in 2017/2018. Recent increases do to doubling in Asian Americans from 3.3% to 6.6%. https://t.co/IBa3fOt83c https://t.co/06Ltm0FycI

Links

Trends in Prevalence of Gout Among US Asian Adults, 2011-2018 https://buff.ly/P39VF1A

Lupus Nephritis

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Procalcitonin > 0.9 ng/mL can be a critical marker for identifying bacterial infection in #SLE. Single center stu

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RheumNow

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Procalcitonin > 0.9 ng/mL can be a critical marker for identifying bacterial infection in #SLE. Single center study of 116 juv. SLE pts dx bacterial infx in 17%. Procalcitonin was signif better than others: NLR, PLR, ESR, CRP, LC4R, ferritin (cut offs need to be defined) https://t.co/NAM8xopNW5

"The most difficult thing is the decision to act, the rest is merely tenacity." –Amelia Earhart https://t.co/ANVIvID8q

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RheumNow

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"The most difficult thing is the decision to act, the rest is merely tenacity." –Amelia Earhart https://t.co/ANVIvID8qj

Complex Evolution of RA Management and Outcomes FIRST is a Japanese longitudinal, real-world registry of rheumatoid ar

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RheumNow

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Complex Evolution of RA Management and Outcomes FIRST is a Japanese longitudinal, real-world registry of rheumatoid arthritis (RA) management, and over the last 20 years has shown significantly improved outcomes, yet significant challenges and unmet needs remain. https://t.co/Vqe70WAijN

Never argue in the chart – call the doctor to resolve the issue.

Submitted by mpetri@jhmi.edu on 4 May 2025

Read more about Never argue in the chart – call the doctor to resolve the issue.

PETRI-ISMS:
"Never argue in the chart – call the doctor to resolve the issue." - Dr. Michelle Petri

Topics

DANBIO registry study of 720 RA pts w/ a prior solid cancer (breast, colon. lung, endometrial, melanoma, bladder) in rem

45 southern African American SLE pts compared to multiethnic cSLE, AA pts had signif higher Dz activity & greater da

Rheumatologist Survey: What do you rely on to diagnose neuropsychiatric lupus (cerebritis)?

2023 report from US NHANES study says #Gout affects 12.1 million in the USA. Gout prevalence incr from 3.6% in 2011/12 t

Lupus Nephritis

Which of the following drugs are NOT FDA approved for lupus nephritis (LN)?

The REGENCY trial (obinutuzumab in LN) included which patients?

The end of the LN obinutuzumab study was assessed when?

The obinutuzumab vs placebo (CRR) response in the REGENCY trial was:

The AURORA 1 trial (voclosporin in lupus nephritis (LN) included which patients?

The primary endpoint of the AURORA 1 trial was a complete renal response (CRR), defined as:

The most frequent serious adverse event in AURORA 1 trial was:

Voclosporin is what kind of drug?

In which lupus patients would you use voclosporin?

I am a...

Are you a Rheumatologist?

Procalcitonin > 0.9 ng/mL can be a critical marker for identifying bacterial infection in #SLE. Single center stu

"The most difficult thing is the decision to act, the rest is merely tenacity." –Amelia Earhart https://t.co/ANVIvID8q

Complex Evolution of RA Management and Outcomes FIRST is a Japanese longitudinal, real-world registry of rheumatoid ar

Never argue in the chart – call the doctor to resolve the issue.

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