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Full read review of Hydryoxychloroquine -its pharmacology, MOA (eg, blocking TLR 7 & 9), Dz specific efficacy and ad

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Dr. John Cush
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Full read review of Hydryoxychloroquine -its pharmacology, MOA (eg, blocking TLR 7 & 9), Dz specific efficacy and adverse effects https://t.co/WVErW1RrCj https://t.co/eQVFIZNSRx
Intraarticular Steroids in OA Lowers Need for Pain Meds

Is it possible that intra-articular corticosteroid injections for osteoarthritis might affect the use of opioids?

British patients with osteoarthritis (OA) who received intra-articular corticosteroid injections had less usage of opioid-containing drugs and other painkillers for years afterward, researchers said.

Bubble Trouble - When Bullous Lupus Bursts onto the SLE Scene Presentation by Dr. Alana Haussmann at the Rheumatology

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Dr. John Cush
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Bubble Trouble - When Bullous Lupus Bursts onto the SLE Scene Presentation by Dr. Alana Haussmann at the Rheumatology Winter Clinical Symposia - Feb 2025 https://t.co/LRsT1TLEm4 https://t.co/bSi50pDn2O

Opioid Deaths are Down (2.28.2025) Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.

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Dr. John Cush
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Opioid Deaths are Down (2.28.2025) Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow. Opioid deaths are down, IL-33 levels are up and Weight loss is in the news again this week! https://t.co/Lb6F64AlNJ https://t.co/7AjSXOn142

Loss of Good Sleep Linked to All-Cause Mortality A US study shows that nearly two-thirds of the population had subopti

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Dr. John Cush
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Loss of Good Sleep Linked to All-Cause Mortality A US study shows that nearly two-thirds of the population had suboptimal 5-year sleep duration trajectories with a resultant 29% increase in risk of all-cause mortality. https://t.co/GXkIDC2uSQ https://t.co/wYzpnK9BMQ

Recurrent Pericarditis in Lupus A study from the Lupus Hopkins Cohort shows that systemic lupus erythematosus (SLE) pa

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Dr. John Cush
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Recurrent Pericarditis in Lupus A study from the Lupus Hopkins Cohort shows that systemic lupus erythematosus (SLE) patients with pericarditis are at risk for recurrence, and likely to be younger patients, with uncontrolled disease, and linkage to higher doses of oral… https://t.co/hML8NfhBy3 https://t.co/cKX5KaSg3a

Risk of Cancer on JAKi in RA (12 463 vs 38 345 controls). No incr risk of CA w/ exposure to JAKi (adj OR 1.04), TNF

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Dr. John Cush
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Risk of Cancer on JAKi in RA (12 463 vs 38 345 controls). No incr risk of CA w/ exposure to JAKi (adj OR 1.04), TNFi (0.98), other bDMARDs (0.98). But JAKi was assoc w/ signif more lung CA (1.40; esp in males 2.12) & less breast CA (0.62) in women https://t.co/fr3VjPhJve https://t.co/zNehdWBbeI

Selective mutation of Traf1/cIAP2 (V196) interaction attenuates inflammatory responses that may contribute to rheumatoid

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Dr. John Cush
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Selective mutation of Traf1/cIAP2 (V196) interaction attenuates inflammatory responses that may contribute to rheumatoid arthritis activity. THis may lead to a new class of therapies for RA https://t.co/kYqAqGsSEA https://t.co/JWUN6iTvxa
Early Hydroxychloroquine Slows Cutaneous Lupus Progression
A prospective study of patients with limited cutaneous lupus erythematosus shows that early introduction of hydroxychloroquine may prevent progression to systemic lupus erythematosus.
SOCS1 Insufficiency - a Rare Inborn Error of Immunity
Lancet Rheumatology has published a population study of the rare suppressor of cytokine signalling 1 (SOCS1) insufficiency - an inborn error of immunity affecting the negative regulation of cytokine and growth factor signalling.
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