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ACR Concerns on the Scientific Integrity at the CDC On behalf of the American College of Rheumatology (ACR), we expres

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Dr. John Cush
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ACR Concerns on the Scientific Integrity at the CDC On behalf of the American College of Rheumatology (ACR), we express deep concern over recent developments at the Centers for Disease Control and Prevention (CDC) that appear to undermine the agency’s longstanding commitment to https://t.co/P2J7eZN07W
APLAR 2025: What’s New in RA Management?
The unveiling of the updated 2025 recommendations for RA treatment, presented by Josef Smolen in the plenary session on the first day of the conference, sparked attention. Although not yet formally published, these updated recommendations represent a refined consensus that simplifies decision-making while reinforcing the importance of treat-to-target principles in RA.
Addressing Disparities and Unequal Burdens in ILD
Interstitial lung diseases (ILDs) represent a complex spectrum of conditions that share one  unifying truth: they are almost always serious, progressive, and life-altering. But for many patients,  the burden of disease does not fall evenly. We are increasingly learning that where you live, who  you are, and the resources available to you, can strongly influence how ILD develops and  worsens. Understanding these disparities is not about pointing fingers. Rather, it is about uncovering opportunities to deliver better, fairer care.

Study of 607 systemic sclerosis (SSc) pts finds Pulm arterial HTN (PAH) in 77 (12.7%). While early immunosuppression did

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Dr. John Cush
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Study of 607 systemic sclerosis (SSc) pts finds Pulm arterial HTN (PAH) in 77 (12.7%). While early immunosuppression didnt reduce odds of PAH (OR 0.74, p=0.495), early mycophenolate was protective(OR 0.12; p=0.048). Only HCQ use signif. improved survival (HR 0.04; p= 0.004). https://t.co/DbsJVZ16Zd

Future Treatment of ILD

In your rheumatic patients with ILD, who usually treats the ILD?

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What determines which patients will be treated for ILD?

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Which class of drugs do you most rely on in treating ILD:

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Patients with ILD – what Immunosuppressants do you rely on?

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With Autoimmune disease and ILD - what is the value of antifibrotics or IL-6 inhibitors?

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What is the value of immunosuppressants (eg MMF) in ILD?

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I treat autoimmune related ILD, because these patients have:

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Which Guidelines for ILD in systemic autoimmune rheumatic disease (SARD) are you familiar with:

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Which drug is proven to be “anti-fibrotic”?

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Which is your practice setting?

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Please select:

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Lung Cancer in Rheumatoid Arthritis and Interstitial Lung Disease A matched cohort study from the Veterans Health Admini

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Dr. John Cush
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Lung Cancer in Rheumatoid Arthritis and Interstitial Lung Disease A matched cohort study from the Veterans Health Administration shows that RA patients have a >50% increased risk of lung cancer, a 3-fold higher risk of lung cancer in RA-ILD. https://t.co/Gjn2M2CNAO https://t.co/DPgDQsCWK9

Combined Therapy in Rheumatoid Arthritis Interstitial Lung Disease RA-ILD is a major therapeutic evidence gap in treat

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Dr. John Cush
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Combined Therapy in Rheumatoid Arthritis Interstitial Lung Disease RA-ILD is a major therapeutic evidence gap in treatment, affecting 8% of patients. It was often under-diagnosed, leading to more severe cases and inflated mortality rates. Despite advancements, RA-ILD, https://t.co/sSzMvDUMf5

Retrospective Korean study of #RA & ILD pts (n 151) - ILD duration & UIP pattern significantly affected prognos

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Dr. John Cush
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Retrospective Korean study of #RA & ILD pts (n 151) - ILD duration & UIP pattern significantly affected prognosis. 62% were non-smokers, DAS28=4.9, UIP in 60%. @4 years, ILD progressed in 58%; mortality=21%. MTX did not affect progression or mortality. https://t.co/1XNcWsAuea https://t.co/QLod6uj2Dj

Elevated serum levels of interleukin-18 discriminate Still's disease from other autoinflammatory conditions. Sera from 5

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Dr. John Cush
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Elevated serum levels of interleukin-18 discriminate Still's disease from other autoinflammatory conditions. Sera from 53 mSAID, 220 guSAID, 49 controls show IL-18 signif increased in Still's Dz; free IL-18 levels were selectively higher in Still's disease. https://t.co/8IWXWZmWgE
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