17 July 2025

Zasocitinib (Tyk2 Inhibitor) Efficacy in Psoriatic Arthritis

A highly selective, tyrosine kinase 2 inhibitor zasocitinib (TAK-279), was studied in a phase 2b trial and found to be effective and safe patients with active psoriatic arthritis (PsA).

French Teratology Service study of 57 pregnant women exposed to anti-IL-1 (47% for Stills Dz) found no evidence of adver

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French Teratology Service study of 57 pregnant women exposed to anti-IL-1 (47% for Stills Dz) found no evidence of adverse pregnancy outcomes with IL-1 inhibition (43 anakinra, 5 canakinumab) 85% livebirths, 11% early miscarriages. Major congenital malformations 3% https://t.co/iyLvaNKA2o

Manifestations and Treatment in Relapsing Polychondritis A large multicenter cohort study of Relapsing Polychondritis (

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Manifestations and Treatment in Relapsing Polychondritis A large multicenter cohort study of Relapsing Polychondritis (RP) describes the clinical manifestations and treatment approaches to this rare, heterogeneous, multisystem disease. https://t.co/Gz2qwtC4jZ https://t.co/ZLkjNQmbRC

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Manifestations and Treatment in Relapsing Polychondritis | RheumNow https://buff.ly/6rLa0nv

Variability of Guidelines on the Perioperative Use of DMARDs in Rheumatic Diseases Patients More effective treatments i

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Variability of Guidelines on the Perioperative Use of DMARDs in Rheumatic Diseases Patients More effective treatments in patients with rheumatic diseases have resulted in less need for major surgery, yet a substantial number of RMD patients will undergo surgery often in the https://t.co/gjJOjZhSHU

Stroke in patients with SLE is associated with a poorer outcome than matched controls in terms of functional recovery, r

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Stroke in patients with SLE is associated with a poorer outcome than matched controls in terms of functional recovery, recurrence, and mortality - study of 40 SLE vs 120 controls w/ CVA https://t.co/spBT1u6bfj https://t.co/eVNYBogJWz

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Full read overview of new imaging modalities for inflammatory arthritis, including high-res.quantitative CT, ultra-high

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Full read overview of new imaging modalities for inflammatory arthritis, including high-res.quantitative CT, ultra-high field MRI), PET, fluorescence optical imaging, optoacoustic imaging, contrast-enhanced ultrasonography - all with artificial intelligence analysis https://t.co/3w5RZEUC9K

17 July 2025

Americans choose short term relief for neck and back pain

New survey data from the Orlando Health Spine Center reveals a significant difference among Americans on how to manage neck and back pain. Respondents were split between relying on rest and reduced activity (44%), turning to over-the-counter pain relievers (42%), and hot/cold therapies (29%) — an uncertainty that may be discouraging some from seeking medical guidance.

SSB, > SSA, Abs are signif associated w/ abnormal DLCO (AUC 0.791) in Sjogrens syndrome, esp in assoc. w/ LIP- lympho

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SSB, > SSA, Abs are signif associated w/ abnormal DLCO (AUC 0.791) in Sjogrens syndrome, esp in assoc. w/ LIP- lymphocytic interstitial pneumonitis. These findings more likely in quadruple positive Sjogrens w/ RF/ANA/SSA/SSB positivity. https://t.co/s6IyRzfXiN https://t.co/J3bMowsrUQ

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https://buff.ly/rNXD3T5

Metanalysis of Uveitis & JIA - 28 studies, 22,834 JIA pts w/ 3,381dx w/ uveitis - prevalence = 12.7%,, highest in Eu

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Metanalysis of Uveitis & JIA - 28 studies, 22,834 JIA pts w/ 3,381dx w/ uveitis - prevalence = 12.7%,, highest in Europeans (14.3%), lowest in Asian (6.5%). Uveitis risk factors included early age JIA onset, ANA-positive, and increased ESR. https://t.co/MxffJKvbik https://t.co/LDz60uwQTM

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The incidence and risk factors of uveitis in children with juvenile idiopathic … https://buff.ly/gMWq45v

16 July 2025

Molecular profiling of RA synovium predicts biologic responses

Machine learning analysis of pre-treatment synovial tissue biopsy from rheumatoid arthritis (RA) patients starting either etanercept (ETN), tocilizumab (TCZ) and rituximab (RTX) revealed high accuracy prediction of 16 week outcomes unique to each biologic.

As nearly 40% of patients with rheumatoid arthritis do not respond to individual biologic therapies, there is the need for predictive biomarkers.

Topics

Zasocitinib (Tyk2 Inhibitor) Efficacy in Psoriatic Arthritis

French Teratology Service study of 57 pregnant women exposed to anti-IL-1 (47% for Stills Dz) found no evidence of adver

Manifestations and Treatment in Relapsing Polychondritis A large multicenter cohort study of Relapsing Polychondritis (

Variability of Guidelines on the Perioperative Use of DMARDs in Rheumatic Diseases Patients More effective treatments i

Stroke in patients with SLE is associated with a poorer outcome than matched controls in terms of functional recovery, r

Full read overview of new imaging modalities for inflammatory arthritis, including high-res.quantitative CT, ultra-high

SSB, > SSA, Abs are signif associated w/ abnormal DLCO (AUC 0.791) in Sjogrens syndrome, esp in assoc. w/ LIP- lympho

Metanalysis of Uveitis & JIA - 28 studies, 22,834 JIA pts w/ 3,381dx w/ uveitis - prevalence = 12.7%,, highest in Eu

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