"Physicians don’t hate technology – they have smartphones, fitness trackers and tablets just like everyone else – what they hate is bad technology."
Truth. #fightburnout
https://t.co/qTG0jZFtDL
Gabe Charbonneau, MD @gabrieldane ( View Tweet)
Analysis of retail pharmacies and drug costs show that, compared to large chain pharmacies, big box was 48% cheaper, followed by grocery-based (18% cheaper), next small chain (51% higher), and independent pharmacies (61% higher) https://t.co/jlQnNboiAR
Dr. John Cush @RheumNow ( View Tweet)
MotherToBaby Pregnancy Study in 528 RA pts has shown oral steroid use yields a dose dependent risk of pre-term birth. PTB was increased high dose (RR: 4.77) and medium dose (aRR: 1.81) OCS in the 1st 139 gestational days; DMARDs/biologics were not https://t.co/cuggovK8eL
Dr. John Cush @RheumNow ( View Tweet)
Might Vioxx make a backdoor comeback? 2017 Vioxx went off patent, now a small pharma has applied to the FDA for orphan drug approval of rofecoxib (& etoricoxib) to treat hemophiliac arthropathy (large unmet need). Say it aint so! https://t.co/kENHHhcyIT https://t.co/QpDNiaCZyz
Links:
Dr. John Cush @RheumNow ( View Tweet)
Choi and colleagues have shown that allopurinol-associated severe cutaneous adverse reactions are higher with Heart (RR 1.44) and Renal (11 fold) disease. Initating low-dosage allopurinol may substantially mitigate this risk. https://t.co/gyj7Xn3uhx
Dr. John Cush @RheumNow ( View Tweet)
Claims study of RA, PsA, AS/SpA patients on TNF inhibitors shows a comparison of 31,527 MTX vs 34,651 TNFi initiators. MTX was D/C sooner in PsA & AS [aHR 1.10, 1.23) vs RA pts. Concomitant MTX reduced risk of TNFi D/C in all [aHR 0.85, 0.81, 0.79] https://t.co/0l2J2FDsUm
Dr. John Cush @RheumNow ( View Tweet)
N. Zealand study shows their cost of knee OA was $200 million in 2013; and without any changes in the standards of care, this isprojected to increase to $370 million by 2038. (includes an additional 4,000 TKRs per year by 2038). https://t.co/B1awh1ky1B
Dr. John Cush @RheumNow ( View Tweet)
Get the FREE RheumaKnowledgy Card - a pocket guide/aid to the diagnosis, testing and Rx of Rheumatologic, autoimmune and other MSK complaints. https://t.co/oMa3qzh7xt
Dr. John Cush @RheumNow ( View Tweet)
NEJM: Synovial Chondromatosis. A 46-year-old woman with rheumatoid arthritis presented with pain and swelling in both knees. Radiographic findings were consistent with synovial chondromatosis. https://t.co/9jMzE0fuNE
Links:
Dr. John Cush @RheumNow ( View Tweet)
The RheumNow Podcast is up! Women are Taking Over Rheumatology. Watch is on the website>> https://t.co/YuDVm1lLXZ or listen to thoe podcast on iTunes, Stitcher, Overcast or SoundCloud >> https://t.co/A8FzdUaEk2
Links:
Dr. John Cush @RheumNow ( View Tweet)
Looking forward to giving plenary talk at #ACR2019 at 11AM Sunday on practical aspects of vaccines(flu/pneumo/VZV) for autoimmune pts @paijournal @IDSA @RheumNow @HealioRheum @AdamJBrownMD @ELittlejohnDO @RulaHajjAliMD https://t.co/UIYBIBDeSe
Leonard Calabrese @LCalabreseDO ( View Tweet)
T2T in Lupus Nephritis aims for less proteinuria, Study of 87 pts with class III/IV LN compared goal of urine protein/creat ratio(UPCR) < 0.5 to stringent < 0.15, Latter assoc w/ lower renal flares (HR 0.16), less CKD (HR 0.19), more MMF use (HR = 7.26) https://t.co/0LSXTiUAaV
Dr. John Cush @RheumNow ( View Tweet)
Take the Good with the Bad? Study of 179 RA pts achieving remission on TCZ- SC 162 mg qwk randomized to continue qWk or space out to q2Wk -- Weekly Actemra better maintained remission (90% versus 73%; P = 0.004), but then again 73% did well w/ spacing EOW. https://t.co/Tcb2WwCbc2
Links:
Dr. John Cush @RheumNow ( View Tweet)
2/ ...but practicing docs use such criteria to:
1. Diagnose patients in clinical practice
2. Teach disease definitions to trainees
Perhaps we should stop making classification criteria entirely and just accept that the field needs diagnostic criteria instead? I
Mike Putman @EBRheum ( View Tweet)
Arthritis Care & Research Editors Pick: Impact of Patient's Global Assessment on Achieving Remission in Patients With Rheumatoid Arthritis: A Multinational Study Using the METEOR Database → https://t.co/wWjIrVHqqJ
Links:
American College of Rheumatology @ACRheum ( View Tweet)