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Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Insights
Read the full article on #RheumNow
https://t.co/294Au0Q1c3 https://t.co/c1X2T5G4jW
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Dr. John Cush @RheumNow ( View Tweet )
2 days 23 hours ago
RECOVERY study of hospitalized COVID-19 pts compared colchicine to PBO (+usual care). Colchicine had no effect on 28d mortality (21% vs 21%), time to D/C(10 d vs 10d), LIve D/C (70 vs 70%), mechanical vent or death (25 vs 25%) https://t.co/dYZglKzwxC
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Dr. John Cush @RheumNow ( View Tweet )
3 days 1 hour ago
Nice full read review of IL-23 in Rheumatology - its biology and clinical targeting. IL-23 is a coordinating cytokine in psoriasis, psoriatic arthritis and inflammatory bowel disease. https://t.co/tDWZuV6Tao
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Dr. John Cush @RheumNow ( View Tweet )
3 days 1 hour ago
Propensity matched comparison of Tramadol vs Codeine use. Tramadol had a signif. higher risk of all-cause mortality (HR, 2.31), CV events (HR 1.15) & fractures (HR 1.50), but no diff in falls, delirium, constipation, opioid abuse, sleep disorders. https://t.co/nBUe5VV1D3 https://t.co/DHzrXQ2nr1
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Dr. John Cush @RheumNow ( View Tweet )
3 days 2 hours ago
September’s most popular read:
11 Drugs That Cause Arthritis
https://t.co/GsV0Qj9ENr https://t.co/DNI9bqgKym
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Dr. John Cush @RheumNow ( View Tweet )
3 days 21 hours ago
In PsA trials, over time the (ACR20) placebo response has increased (15% every 5 yrs)but was not associated with the active treatment effect size. 42 RCTs, the pooled placebo response was 20.3%; pooled treatment effect vs placebo was 27% https://t.co/b9LRpvcTir
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Dr. John Cush @RheumNow ( View Tweet )
3 days 23 hours ago
Adalimumab biosimilar AVT02 equivalent to Originator Humira in Moderate to Severe Chronic Plaque Psoriasis patients with a PASI score at Week 16 of 91.6% for AVT02vs 89.6% for Humira https://t.co/dO4g4aOuON
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Dr. John Cush @RheumNow ( View Tweet )
4 days ago
ICYMI: Drug Safety Risk Communication- The 800 lb Gorilla Approach | #RheumNow https://t.co/6iSJjvlFF8 https://t.co/6egrpCVuaG
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Dr. John Cush @RheumNow ( View Tweet )
4 days 1 hour ago
ICYMI: Steroid Poker
https://t.co/kJOmCyIpzM https://t.co/A6EkxcIcHG
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Dr. John Cush @RheumNow ( View Tweet )
4 days 2 hours ago
In a real world study of lupus patients, aspirin use lowered risk of preeclampsia, as did hydroxychloroquine. Risk Factors for preeclampsia were high Dz activity 1st trimester (OR 4.55), BMI >30 (6.14), antiphospholipid synd (8.02), hx preeclampsia (9.8)https://t.co/giBamMAPRM
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Dr. John Cush @RheumNow ( View Tweet )
4 days 21 hours ago
JAMA reports the COVID-19 combined infection- and vaccination-induced seroprevalence estimate in May 2021 was 83.3% By May 2021, there were 2.1 SARS-CoV-2 infections per reported COVID-19 case. https://t.co/bUZ5AqYnxM
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Dr. John Cush @RheumNow ( View Tweet )
4 days 22 hours ago
Pregabalin (lyrica) for Fibromyalgia 75 mg bid; may be increased to max dose 450 mg/d. (Reduce for renal dz). Indications: DM neuropathy/pain, post-herpetic neuralgia, partial seizures. Rare AE: Angioedema, low Plts, ^PR interval, rhabdo, gynecomastia https://t.co/r4cH7n9qWD
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Dr. John Cush @RheumNow ( View Tweet )
5 days 20 hours ago