RNL Replay: Vasculitis Be sure to sign up for this week's TNR: Vasculitis Mavens on Tuesday April 16th at 6:30pm EST. Rituximab and cyclophosphamide are equally effective for induction in severe GPA. Choices True False Which of the following carries the highest weight (most points) in the 2022 ACR/EULAR classification criteria for GPA? Choices Nasal crusting Sensorineural hearing loss Pauci-immune glomerulonephritis on biopsy Positive test for PR3 Plasma Exchange (PLEX) is routinely recommended for active glomerulonephritis (GN) in GPA management. Choices True False For maintenance of remission in GPA, azathioprine is more effective than rituximab. Choices True False What is the initial treatment approach for newly diagnosed cases of GCA without visual symptoms? Choices Tocilizumab 162 mg SC weekly Intravenous methylprednisolone 1g for 3 days Prednisone 40-60 mg/d Cyclophosphamide For patients with suspected GCA temporal artery biopsy is conditionally recommended over temporal artery ultrasound for establishing a diagnosis of GCA. Choices True False Trimethoprim sulfamethoxazole prophylaxis is used in GPA patients treated with rituximab because TMP/SMX: Choices Decreases PJP infection Decreases serious infections Decreases outpatient infections All the above For patients with eosinophilic granulomatosis with polyangiitis (EGPA) presenting with respiratory symptoms (wheezing, chest tightness), which treatment is recommended? Choices Intravenous cyclophosphamide Mepolizumab High-dose glucocorticoids Azathioprine Select one Choices I am a rheumtologist I am a fellow/trainee I am an NP/PA Other Join us for this week's TNR, RNL Replay Vasculitis Mavens