Articles By Jack Cush, MD
Abatacept Efficacy in JIA
Subcutaneous abatacept (Orencia) showed efficacy among children with polyarticular juvenile idiopathic arthritis (JIA) in an open-label phase III trial.
Read Article
Severe Stevens-Johnson and Toxic Epidermal Necrolysis Syndromes May Respond to Etanercept
The Journal of Clinical Investigation reports the results of a trial wherein etanercept (ETN) was shown to be effective in treating cytotoxic T lymphocyte–mediated (CTL-mediated) severe cutaneous adverse reactions (SCARs), including Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (T
Read Article
Leflunomide May Sensitize the Insulin Receptor and Have an Anti-Glycemic Effect
An animal model study in the Journal of Endocrinololgy reports the potential use of leflunomide in the control of hyperglycemia in male mice.
Read Article
The RheumNow Week in Review - 2 March 2018
Dr. Jack Cush reviews the news and highlights from the past week on RheumNow.com.
Read Article
Steroid Use During Rheumatoid Pregnancies
Pregnant women (n=254) with rheumatoid arthritis who enrolled in the MotherToBaby Autoimmune Diseases in Pregnancy Study and who were taking oral glucocorticoids were studied.
Read Article
Diet During Pregnancy May Influence Future Allergic or Autoimmune Disease
A systematic review of the literature on the relationship between diet during pregnancy, lactation, or the first year of life suggests that maternal ingestion of probiotic and fish oil supplementation may reduce risk of eczema and allergic sensitization to food, respectively.
Read Article
Hip Replacement Augments Longevity
Data from Swedish hip replacement registry finds that total hip arthroplasty not only improves quality of life, it is also associated with increased life expectancy that lasts for 10 years after surgery, especially in primary osteoarthritis patients.
Read Article
Inflammatory Arthritis Variants with Checkpoint Inhibitors
Capelli and colleagues have studied patients treated with ICIs and found two variants of inflammatory arthritis (IA) - a reactive arthritis like large joint arthritis with combination ICI therapy or a small joint IA with ICI monotherapy.
Read Article
2017 Rheumatology Year in Review
This retrospective review is drawn from the authors collection of the most impactful publications, research and news that occurred in 2017. In no particular order, here are my top rheumatology advances, news and research reports for calendar year 2017.
Read Article
Gout Crystal Deposition is Deeper than its Measures
Dalbeth and colleagues have published that among gout patients without palpable tophic and despite long term allopurinol, nearly half have monosodium urate (MSU) as detected by Dual-energy CT (DECT). The total body urate deposition is even greater in those with higher sUA and evidence
Read Article
