Articles By Jack Cush, MD
Smoking Worsens Rheumatoid Inflammation
Tobacco and chronic smoking is a major risk factor for the onset of rheumatoid arthritis (RA), and chronic smoking has been linked to severity of disease and lower DMARD response rates.
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Autoimmune Disease as Harbinger of Myelodysplasia
Myelodysplastic syndrome may infrequently present with inflammatory or autoimmune symptoms. This literature review shows a variety of presentations and treatment options for such patients.
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Rheumatologists May be Unaware of New Hydroxychloroquine Retinopathy Monitoring Guidelines
Rheumatologists are well-acquainted with the rules for hydroxychloroquine (HCQ) retinopathy screening: A) annual visits to the ophthalmologist and B) maintain HCQ doses at less than 6.5 mg/kg to avoid retinopathy.
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RheumNow Week in Review – 12 August 2016
Watch Dr. Cush review 13 highlights from this week on RheumNow.
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Consensus Recommendations for Juvenile Dermatomyositis
SHARE (Single Hub and Access point for pediatric Rheumatology in Europe) is a group established in 2012 to develop and optimize diagnostic and management regimens in Europe for children and young adults with rheumatic diseases.
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Etanercept May Lower Alzheimers Risk in Rheumatoid Arthritis
The pathogenesis of Alzheimer's disease (AD) is unknown but some have speculated a role for inflammation.
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Cryptochromes Regulate Circadian Inflammation
Circadian rhythms may be disrupted or become exaggerated in a variety of inflammatory conditions. For instance, interleukin-6 (IL-6) and IL-1 have a known circadian cycle to their production, but the same can not be said for TNF.
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EULAR Updates Gout Guidelines
A EULAR task force of 24 individuals (including 15 rheumatologists) have updated their previous 2006 guidelines for gout. The current update, which includes 11 recommendations, is based on a systematic literature review and a Delphi consensus approach to recommendations.
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RheumNow Week in Review – 5 August 2016
Highlights from this week on RheumNow.com include: 1. Having #RA in addition to solid cancer (breast, lung, prostate, colon) increases mortality rates by 40-50% in elders https://t.co/aitjusmOai 2. The global market for rheumatoid arthritis therapies was $19.9 billion in 2015, expected to reach $21.3B by 2020 https://t.co/d2Sh5C8y9f 3. Half of doctors never heard of MACRA:Medicare Access & CHIP Reauthorization Act. Starts on Jan 1st! https://t.co/eYgWBWCw6y Blog:https://t.co/sRKZSOFyNV And more!
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Serious Infections are Not Increased in HIV Patients Treated with TNF Inhibitors
Infections are a concern for many when using tumor necrosis factor-α inhibitor (TNFi) therapy to treat inflammatory disorders. Even moreso in those at higher risk.
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