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Articles By Jack Cush, MD

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Ixekizumab Superior to Etanercept in Psoriasis

The UNCOVER-2 and UNCOVER-3 trials were presented at the American Academy of Dermatology (AAD) Annual Meeting taking this week in Washington, D.C.

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Vitamin D has No Effect on Knee Osteoarthritis

Vitamin D supplementation for individuals with knee osteoarthritis and low 25-hydroxyvitamin D levels did not reduce knee pain or slow cartilage loss, according to a study appearing in the March 8 issue of JAMA.  

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Novel Protein as a Potential Autoantigen in JIA

Juvenile idiopathic arthritis (JIA) is clearly not related to rheumatoid arthritis and until recently has no identifiabile autoantigen linked to JIA.

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Pregnancies are Adversely Affected Even Before the Diagnosis of Lupus

Arkema and colleagues assessed maternal and fetal outcomes in patients with SLE, pre-clinical (prior to onset) SLE and prevalent maternal SLE during pregnancy compared with the general population.

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The Week in Review - 4 March 2016

Highlights from this week on RheumNow:

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Intraarticular Steroids Before Joint Surgery Increase Infection Risk

Hip and knee intraarticular injection of corticosteroids are frequently prescribed to alleviate pain or inflammation in patients with osteoarthritis and rheumatoid arthritis, especially in the period leading up to scheduled arthroplasty.

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AAOS Guidelines on Carpal Tunnel Diagnosis

Three million Americans are diagnosed with carpal tunnel syndrome each year. 

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Methotrexate Safety with Chronic Hepatitis B Infection

Chronic liver disease, and in particular hepatitis B infection, is a contraindication to methotrexate (MTX) use.

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TNF Inhibition and Heart Failure

Clinicians often face the issue of using a TNF inhibitor (TNFi) in patients with heart failure or cardiac disease. Here are the facts and data necessary to make a cogent decision to use or avoid TNFi.

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Early Aggressive Treatment of Elderly RA Results in Less Joint Surgery

Two  population-based cohorts from Ontario (ON) and Quebec (QC) were used to assess if early DMARD influenced the need for joint replacement surgery among elderly patients with incident rheumatoid arthritis.

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