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Articles By Jack Cush, MD

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PML is Very Rare in Lupus

A systematic review of the literature was done to assess the relationship between immunosuppressive therapy, adult systemic lupus erythematosus (SLE) and the onset of progressive multifocal leukoencephalopathy.

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ASBMR Guidance on Bisphosphonate Use

The American Society of Bone and Mineral Research (ASBMR) Task Force has issued a guidance report on the use of bisphosphonates (BP) with a focus on the risk vs. benefits of such therapy. (Citation source http://buff.ly/1Nn0CVb)

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10 Ways Rheumatoid Arthritis Could’ve Killed Glenn Frey

I was truly stunned Monday when it was announced that Glenn Frey, from the Eagles, had died as a result of complications from his rheumatoid arthritis, ulcerative colitis and pneumonia.

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Methotrexate Nonadherence is Common

Researchers from Belgium studied patient adherence to MTX (given orally or via injection) in 129 rheumatoid arthritis (RA) patients over a 16-week period using an electronic monitoring system and two validated adherence questionnaires.

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French Cannibinoid Phase I Study Gone Wrong

Six volunteers were admitted to the University Hospital of Rennes in France last week after partaking in the Phase I trial of a new medication meant to treat mood disorders such as anxiety.

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DSB Reports & Updates - January 2016

Comparative Harmful Risks with Targeted Immunomodulators. Desai et al did a systematic review of the literature, findings of 10 head-to-head RCTs and 51 observational studies.

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MRI Bone Marrow Lesions Predict Worse Outcomes in Osteoarthritis

Medical Research Council study shows MRI lesions may predict which patients will have more rapidly progressing osteoarthritis. 

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Mosquito Born Zika Virus Affects Caribbean and Latin America

The Centers for Disease Control and Prevention (CDC) has issued a travel advisory for individuals traveling to the Caribbean and Latin America where infection with Zika virus has been prevalent.

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FDA Approves Cosentyx for Ankylosing Spondylitis and Psoriatic Arthritis

Cosentyx (secukinumab) was approved by the FDA on 15 January, 2016 for patients with active ankyosing spondylitis (AS) and psoriatic arthritis (PsA).

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BSR Issues DMARD Prescribing Guidelines for Pregnancy

Treatment paradigms for managing pregnancy in rheumatoid arthritis (RA) have been challenged in recent years with the introduction of new agents and reclassification of drug safety during pregnancy by the FDA.

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