Articles By Jack Cush, MD
FDA Panel Votes 10-4 to Approve Lesinurad for the Treatment of Hyperuricemia/Gout
Despite concerns over safety, the FDA Arthritis Advisory Committee voted favorably to approve lesinurad (LES) at a meeting held Friday, October 23, 2015. Overall, panel members felt the potential benefits of LES outweighed the safety concerns reviewed by the FDA presenters.
Read Article
Vertebral Fractures in 10% of Spondyloarthritis Patients
Vertebral fractures are not uncommon in patients with ankylosing spondylitis and spondyloarthritis.
Read Article
IV Cyclophosphamide Equal to Mycophenolate in Lupus Nephritis
A comparison of mycophenolate mofetil (MMF) and low-dose cyclophosphamide IV (CYC) in the treatment of lupus nephritis (LN) was examined in 173 patients with class III, IV, or V LN.
Read Article
Increasing Placebo Responses in the USA
A recent analysis of randomized clincal trials (RCT) for the treatment of neuropathic pain has shown in increase in placebo responses. (Citation source http://buff.ly/1LL8yAi)
Read Article
U.S. Pays 10 Times More for Prescription Drugs than Other Countries
Prescription drugs may cost up to 10 times more in the United States than they do in other countries, according to a 2013 Comparative Price Report was released last month by the International Federation of Health Plans (IFHP).
Read Article
FDA Reviews the Safety of Lesinurad in Gout
Lesinurad is a novel URAT-1 inhibitor being developed as a urate-lowering therapy for gout by Astra-Zeneca.
Read Article
Weight Loss Improves Skin Outcomes in Psoriasis
A recent presentation at the European Academy of Dermatology and Venereology (EADV) meeting in Copenhagen showed the long-term outcomes of weight loss in psoriasis.
Read Article
The Best Kind of Arthritis …..Revisited
A reprise of a prior blog on the "best kinds of arthritis" to have. This time with more commentary and good news.
Read Article
Sleep Apnea Increases Risk of Gout
Zhang and colleagues from Boston analyzed patients with physician diagnosed sleep apnea from The Health Improvement Network in the UK and compared these with 5 controls (age, sex, BMI matched). They studied 9,865 patients with sleep apnea and 43,598 controls.
Read Article
Initiation of Urate-Lowering Therapy During Gout Attacks
A retrospective analysis examined whether it's better to initiate urate-lowering therapy (ULT) during or after an attack of acute gout.
Read Article
