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MRI Bone Marrow Lesions Predict Worse Outcomes in Osteoarthritis

Medical Research Council study shows MRI lesions may predict which patients will have more rapidly progressing osteoarthritis. 

The SEKOIA study studied MRI scans of the knees of 176 men and women over 50 years old. They were then followed up for an average of three years with repeated knee X-rays. Individuals with abnormalities on their MRI scans at the first appointment were compared to those without to examine the effect on disease progression.

Individuals with bone marrow lesions (BMLs) on their MRI scan were found to have osteoarthritis that progressed more rapidly than those that did not.  Such change may lead to the need for joint replacement.

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The author has no conflicts of interest to disclose related to this subject