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Articles By Jack Cush, MD

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Romosozumab Surpasses Teraparitide in the STRUCTURE Study

The experimental bone drug, romosozumab, has succeeded in meeting its primary endpoint by showing it was significantly more effective than teriparatide in a 12-month study assessing total hip bone density in postmenopausal women with osteoporosis.  

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Bicycle Injuries and Fatalities Increasing in Older Americans

JAMA reports the number of traumatic injuries related to bikes in adults nearly doubled from 1998 to 2013 -- going from 8,791 to 15,427. The researchers used data from the National Electronic Injury Surveillance System, which includes data from of 100 emergency departments, and U.S.

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Advances in Uveitis Associated with Juvenile Arthritis

Uveitis is a common association of juvenile idiopathic arthritis (JIA) that has previously been characterized by poor visual prognosis with limited options for effective treatment.

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MOST Study: End Stage Knee Osteoarthritis Shows Dynamic Change by MRI

Guermazi and colleagues have investigated whether end-stage knee osteoarthritis (OA), assessed as grade 4 Kellgren and Lawrence (KL) radiographic changes, are really "end stage".   

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Life Expectancy Rises, but People Living Longer with More Illness

Lancet has reported that people are living 6.2 years longer, worldside since 1990.  Yet, there has been a rise in illness and disability,and a complex mix of fatal and non-fatal ailments leading to a large amount of health loss.

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C5orf30 Gene is a Negative Regulator of Tissue Damage in Rheumatoid Arthritis

PNAS has reported the work of an international team of scientists from the University College Dublin and the University of Sheffield, who have studied DNA samples and biopsy samples from joints of over 1,000 rheumatoid arthritis patients in the UK and Ireland and determined the C5orf30 gene to be

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DSB: Drug Shortages August 2015

RheumNow is committed to reporting safety issues in our monthly Drug Safety Bulletins. Each month we will update you with reports of new, ongoing and resolved Drug Shortages that will affect the practicing rheumatologist.

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Increased Vascular Mortality in Ankylosing Spondylitis

Haroon et al has analyzed administrative claims data from Ontario, Canada and compared 21473 AS patients with 86606 normal comparators matched for age, sex, and location of residence.

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Hyperuricemia, Death & Kidney Disease

In a recent study published in the Journal of the American Geriatrics SocietyTaiwan investigators examined the Annual Geriatric Health Examination Program database (2006 to 2010) to estimate the all-cause, cardiovascular, and cancer mortality risks associated with serum uric acid le

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Female "Viagra Pill" Controversy - Grandstanding or Equal Rights?

The FDA is under pressure over the recent approval of the "female viagra" pill.  On August 18th, the FDA announced its approval for Addyi (flibanserin) to treat acquired, generalized hypoactive sexual desire disorder (HSDD) in premenopausal women.

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