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Articles By Jack Cush, MD

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Pick Up the Phone

Inefficient peer-to-peer physician communication has eroded integrated care and compromised patient outcomes and safety. Picking up the smart phone and use of technology may help to close these gaps.

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Xeljanz Warnings on Shingles Updated by FDA

The MedWatch June 2015 safety labeling changes were published yesterday, and updated the warnings for Xeljanz (tofacitinib). "The risk of herpes zoster is increased in patients treated with Xeljanz and appears to be higher in patients treated with Xeljanz in Japan."

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IRB Conflicts of Interest Persist

Committees at academic institutions that make decisions on research and clinical trials may be conflicted, as nearly one-third of IRB members have some ties to the pharmaceutical industry.

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21st Century Cures Act Passes in the House

On Friday, July 10th, the U.S. House voted overwhelmingly to streamline the approval process of prescription drugs and medical devices by the FDA.

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The High Cost and Burden of Sepsis

One million people are hospitalized each year with sepsis. This is more than the number of hospitalizations for heart attack and stroke combined. Sepsis can be a particular risk for older people.

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Factors Affecting Opiate Abuse Identified

Researchers have determined that adults aged 50 and above were more likely to acquire pain relievers through more than one doctor, whereas younger individuals were more likely to acquire them from friends, relatives or drug dealers.

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FDA Strengthens MI and CVA Risks Associated with NSAIDs

FDA announced yesterday they would strengthen warnings  stating that non-aspirin nonsteroidal anti-inflammatory drugs increase the chance of a heart attack or stroke. This applies to both prescription and OTC NSAIDs.

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The Differential Diagnosis of Heel Pain

A slim, yoga bending, middle aged school teacher seeks a rheumatology consultation to determine the cause and cure for her left lateral heel pain for the past 6 months. No trauma, no crazy footwear and no systemic symptoms, uveitis, or peripheral/axial arthritis.

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Health Canada Issues Acetaminophen Advisory

Yesterday Health Canada announced it “is taking additional steps to minimize the risk of liver damage and improve acetaminophen safety,” citing the findings of a government review that underscored the possibility of accidental overdose.

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Does ACPA Increase the Risk of Interstitial Lung Disease?

The anti-citrullinated peptide (anti-CCP or ACPA) antibody assay has a specificity of greater than 90% for rheumatoid arthritis and is associated with worse articular outcomes.

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