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Jack Cush, MD

Dr. Cush is the Executive Editor of RheumNow.com and also Co-Edits the online textbook RheumaKnowledgy.com. 
  
Dr. Cush's interests include medical education, novel drug development, rheumatoid arthritis, spondyloarthritis, drug safety, and Still's disease/autoinflammatory syndromes. He has published over 140 articles and 2 books in rheumatology.
 
He can be followed on twitter: @RheumNow

Articles By Jack Cush, MD

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5 Mistakes When Diagnosing Adult-Onset Still’s Disease

Adult-onset Still's posses a interestng and diagnostic challeng when encountered. Here are 5 tips to improve your diagnostic acumen for this febrile disorder.

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The Best Kind of Arthritis

I was recently asked, “what is the best kind of arthritis to have?” My response is based on diagnosibility, treatability and safety of necessary treatment. 

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The Evolution of Drug Safety

Drug efficacy is swiftly proven in phase II and III trials. Yet drug safety requires time, wider exposure, physician education and patient acceptance to be fully established.

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DECT Evidence of Urate Deposition is Associated with X-ray Damage in Gout

Dalbeth and coworkers studied  92 patients with gout and using DECT scanning have shown those with urate deposition on DECT were 8.5-fold more likely to have erosive disease on plain radiographs.

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Nonadherence to Self-Injected Biologics is High

Researchers from the University of Manchester investigated self-reported adherence to biologic treatment in RA and found that 41% of patients were non-adherent to adalimumab therapy at least once, and 23% were nonadherent overall. http://bit.ly/1KA2

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Osteoporosis Induced by Bariatric Surgery

Although the cause is not clear, women who have weight loss surgery have a higher risk of thinning bones (osteoporosis) and fractures over time, according to a new analysis of a Swedish study.

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Medicare D and Costly Biologics

25% of Medicare beneficiaries with rheumatoid arthritis use high-cost biologics.  Yazdany and coworkers have analyzed a national cohort of beneficiaries and compared Medicare part D plans.

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Prevalence of doctor-diagnosed arthritis and activity limitations

52.5 million US adults (22.7%) have arthritis with half of these claiming activity limitation because of arthritis and pain.  Many arthritis patients have comorbid conditions including heart disease (49%), diabetes (47%) and obesity (31%).

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Annual Review of Rheumatology Advances - 2014

This retrospective highlights several of the most impactful publications, trends, research and news that occurred in 2014.

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Amgen Halts Development of Brodalumab

IL-17 inhibitors are being developed for treatment of psoriasis, psoriatic arthritis and axial spondyloarthritis. Broadalumab has been in phase II & III trials and been developed by a partnership between Amgen and Astra-Zeneca.

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