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Articles By Jack Cush, MD

myositis, polymyositis, wikipedia

Risk Prediction Modeling in MDA5 Dermatomyositis

Patients with Melanoma differentiation-associated gene 5 (MDA5) positive dermatomyositis (DM) are complicated and prone to interstitial lung disease, poor prognosis, and a high mortality.

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Targeting PD-1 in Rheumatoid Arthritis

The results of the large Phase 2b RENOIR trial showed that rosnilimab, a monoclonal antibody targeting PD-1, was effective in moderate-to-severe rheumatoid arthritis (RA) patients.

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AI,machine,learning

Growing Physician Enthusiasm for AI in Healthcare

The AMA has just published the results of a U.S. Physician survey and shown MD attitudes have positively shifted regarding the use of artificial intelligence (AI) in healthcare.

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Valentine RNL 2025 Review (2.14.2025)

Dr. Jack Cush reviews highlights from RheumNow Live 2025 held in Dallas, TX on Feb. 8-9, 2025.

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lupus SLE

Obinutuzumab Efficacy in Active Lupus Nephritis

A phase 3, randomized controlled trial of an anti-CD20 monoclonal antibody, obinutuzumab, was shown to be effective and safe in patients with active lupus nephritis.

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Drug Naming Games (2.7.2025)

Dr. Jack Cush reviews the news, regulatory and journal reports from the past week on RheumNow.com.

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cannabis,weed,marijuana

Cannabis Hospitalizations and Mortality Risk

A Canadian population, retrospective cohort study shows individuals needing hospital-based (emergency department or hospitalization) care for a cannabis use disorder (CUD) were at increased risk of death. 

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Is Rheumatoid Arthritis Becoming Milder?

A 24 year, prospective study analyzing very early rheumatoid arthritis (RA) in three consecutive eras suggests that RA has evolved since 2005, demonstrating less seropositivity, inflammation, and erosions but is characterized by more comorbidity, smoking and corticosteroid use.

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Pain Management in Rheumatoid Arthritis

BMC has published a full read literture review of pharmacological pain management in rheumatoid arthritis, pointing out that the best evidence for pain control comes from the use of DMARDs and treat-to-target strategies.

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BSR Guideline on Management of Sjögren disease

The British Society for Rheumatology has published its guideline for the management of adult and juvenile onset Sjogren's disease. 

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