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Articles By Jack Cush, MD

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Treatment Sequences Define Subphenotypes in RA Patients

An analysis of a large rheumatoid arthritis cohort sheds light on biologic disease-modifying anti-rheumatic drugs (bDMARDs) clustering that may be used in management, as certain clusters of b/tsDMARD correlated with disease activity over time. 

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Are bDMARDs, tsDMARDs and biosimilar DMARDs cost effective?

Treatment advances with new biologic disease-modifying antirheumatic drugs (bDMARDs), targeted synthetic DMARDs (tsDMARDs) and biosimilar DMARDs (bsDMARDs) have proven efficacy and safety; but does their increased cost yield commensurate benefits in patients with rheumatoid arthritis (RA) and high disease activity?

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Cancer Risk From RA, Not the Drugs

While it is known that rheumatoid arthritis (RA) patients may be at risk for certain cancers, the question is which cancers and is this modified by therapy.

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Abatacept Safety Outcomes Across 7 European Registries

A multinational registry analysis of rheumatoid arthritis (RA) receiving abatacept (ABA) has shown that the safety profile of ABA remains unchanged with no new or increased risks of infection or malignancy.

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2023 EULAR Recommendations on Imaging in Crystal-Induced Arthritis

New recommendations on imaging for crystal-induced (gout, CPPD) arthritis (CiA) were presented at EULAR 2023 in Milan.

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How Often Do You Monitor MTX? (6.16.2023)

Dr. Jack Cush reviews the news and journal reports from this past week on RheumNow.com, including new drug approval, a new SpA variant and new rules for methotrexate (MTX) monitoring and depression screening. 

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Higher Genetic Loads Linked to Worse Systemic Lupus

A Korean study of a large systemic lupus erythematosus (SLE) cohort shows by genomic analysis, that higher weighted genetic risk scores (wGRS) is associated with earlier SLE onset, higher anti–Sm antibody positivity, lupus nephritis and more diverse lupus manifestations.

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Why Depression Screening Should be Mandatory at Each Visit

Depression is more widespread than ever in the United States, according to a new study from Gallup, showing that 18% of adults are depressed (or receiving depression treatment for depression) – an increase in 7 percentage points since 2015. 

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High Mortality Rates with Depression in Rheumatoid Arthritis

A Danish cohort study has shown a deadly association between depression and rheumatoid arthritis (RA).  

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Diagnostic Yield of Cranial and Large Vessel Imaging in GCA

Combined cranial and large vessel ultrasound and PET/CT provided excellent accuracy for the diagnosis of giant cell arteritis (GCA).

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