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Articles By Jack Cush, MD

Checklist IgG4

Prevalence and Mortality of IgG4-related disease in the USA

A current review of the epidemiology of IgG4-related disease (IgG4-RD) in the USA shows a low prevalence with possibly increasing numbers, owing to increasing awareness of this unique immune-mediated condition.

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PJP Prophylaxis Needed with Steroids and Rituximab

Pneumocystis jirovecii pneumonia (PJP) can be a life-threatening infection in immunocompromised patients. The 2023 EULAR Vasculitis guidelines recommends primary prophylaxis with antibiotics, especially in rheumatic disease patients receiving rituximab (RTX).

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National Population Insights (4.28.2023)

Dr. Jack Cush reviews the news and journal reports and addresses 3 viewer case questions.

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25 Great Women in Rheumatology

This week I reached out to many leaders in rheumatology and asked: who are the great women in rheumatology who should be recognized? This was prompted by a smart article in Annals of Rheumatic Disease written by Drs. Tuhina Neogi (Boston) and Nicola Dalbeth (N. Zealand), entitled "Where are the women ‘Heroes and Pillars of Rheumatology’?

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Denosumab Reduces Type II Diabetes Risk

The British Medical Journal has publish a matched cohort analysis demonstrating that adults receiving denosumab had a lower risk of incident type 2 diabetes (NIDDM) compared with those taking oral bisphosphonates for osteoporosis.

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A Rising Gout Risk in Asians

Two independent data sets suggests the prevalence of gout among Asians has grown such that this sub-population has numerically surpassed all other racial and ethnic groups by 2018.

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NY Times on Arthritis Prevention

A reader question ("Ask Well") to the New York times wonders "is arthritis avoidable"? A recent survey suggests that up to 60% of adults have been told by an HCP they had some form of arthritis.

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Want to Go Far, Go Together (4.21.2023)

This week on the podcast Dr. Jack Cush reviews the news, regulatory announcements and novel journal reports including a profile on pseudogout, the safety of immune checkpoint inhibitors in RA patients and the diagnostic importance of neutrophils.

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Sex-Specific Differences in Psoriatic Arthritis

A systematic review of published literature on psoriatic arthritis (PsA), clinical features, disease activity, and patient-reported outcomes (PROs) shows generally higher levels of disease activity in women, compared to men with PsA.

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Immune Checkpoint Inhibitor Safety with Pre-existing Rheumatoid Arthritis

Lancet Rheumatology has published a retrospective analysis showing patients receiving immune checkpoint inhibitors (ICI) for cancer have the same outcomes (mortality and severe immune-related adverse events (irAEs)) even when they have pre-existing rheumatoid arthritis (RA).

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