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Christopher Wright, MD

| Jun 26, 2018 2:54 pm

I would like for febuxostat to remain available for the (fairly small in reality) portion of patients who cannot tolerate or have inadequate control with allopurinol. But most of the "allopurinol failures" I see on febuxostat were uptitrated to 400 or maybe 600mg of allopurinol before switching. Febuxostat is extremely over-prescribed by non-rheumatologists in my opinion, so part of me would be glad to see it restricted for that reason.