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Sterling West, MD

| Jan 28, 2016 4:00 pm

I would argue that this patient has hypocomplementemia urticarial vasculitis syndrome associated with anti-C1q antibodies. All the clinical manifestations including arthritis, LCV, pericarditis, hive-like lesions, and GN with full-house pattern have been described in this syndrome (J Clin Aesthet Derm 5: 36-46, 2012). I don't see in their article that they tested for the anti-C1q antibody but this should be done. The importance of making that diagnosis is many of these patients develop COPD not related to smoking and dapsone can be a useful preventative therapy.