Rob, I concur with your critique of the title. I did reword this title to be provacative and make others think about this paper and issue. Without this and with a conservative title of Allopurinil SJS/TENS Events are Enriched in Certain Populations" would have garnered about 12 readers. Prior to reading this I never gave much consideration of B5801 testing - it seemed reserved largely for Han Chinese and other SE Asian populations as a risk factor. The authors conclusion and call for "vigilance in these minorities when considering alcohol" to me speaks for consideration of wider testing or preferably, the need for studies that look into the predictive value first and then cost analyses second (such tests are not cheap as you suggest!). I think thoughtful comments (like yours) and smart research (TBD) are needed on this issue, if not the challenging title. Thanks!