My other criticism of this report is "why did they separate 400 mg from the lower dose range?" We usually use 400 mg a day or less. At 399mg daily and less, there were no increase in congenital anomalies. I'd love to see the data redone using "400 mg a day and less" vs "401 mg a day and more". It may not show any increased risk in congenital problems at all on typical doses used.