My other criticism of this report is "why did they separate 400 mg from the lower dose range?" We usually use 400 mg a day or less. At 399mg daily and less, there were no increase in congenital anomalies. I'd love to see the data redone using "400 mg a day and less" vs "401 mg a day and more". It may not show any increased risk in congenital problems at all on typical doses used.
My other criticism of this report is "why did they separate 400 mg from the lower dose range?" We usually use 400 mg a day or less. At 399mg daily and less, there were no increase in congenital anomalies. I'd love to see the data redone using "400 mg a day and less" vs "401 mg a day and more". It may not show any increased risk in congenital problems at all on typical doses used.