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Gary Botstein

| Dec 01, 2022 9:07 am

the synopsis of these studies seems to indicate these are non-randomized, observational studies which can't possibly control for all the variables that determine whether docs and patients chose to inject or not. It doesn't address the quality of life gained by injections, doesn't answer the question of delayed or avoided total knee replacements, doesn't address the baseline level of activity (ie a 90 year old with OA may be content with limited activity, while a 50 year old may chose injection to maintain or increase level of activity), etc. The question of damage from steroid injections remains unanswered.