RK There's now way of knowing as they only measured IgM RF as part of the Exxelerate trial; and this was a limited subanalysis. But there are other small reports noting that with high RF, there can be Fc binding to mAb TNFi with less efficacy. Reply
RK
There's now way of knowing as they only measured IgM RF as part of the Exxelerate trial; and this was a limited subanalysis. But there are other small reports noting that with high RF, there can be Fc binding to mAb TNFi with less efficacy.