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Canary in a Coal Mine (4.19.2024)

Jack Cush, MD

Dr. Jack Cush reviews regulatory reports, news and novel journal articles - this week focusing on Sjogren's, ILD, Gout and Uveitis.

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BSR Guideline on Management of Sjogren’s Syndrome

Jack Cush, MD

Sjögren disease (SD) is the most common of all autoimmune disease, yet little is know of its etiology and there are insufficient interventions for those affected with mucosal or systemic manifestations. 

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Seo RNL

ICYMI: Vasculitis Pearls

Richard Conway, MBBChBAO, PhD

Once again RheumNow Live 2024 really delivered with high impact learning packed into short sessions. As someone with an interest in vasculitis it was fantastic to see four of my favorite speakers in the Vasculitis Mavens and STEP talks. They gave us what we really want from these talks – personal opinions and approaches that go beyond the guidelines. They really dropped a selection of pearls on us and I wanted to share a few of these with you.

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Biopsy Results in Sjogren's Syndrome

Jack Cush, MD

A prospective study from the Netherlands analyzed the comparative value of simultaneous labial and parotid salivary gland biopsies performed in patients with sicca complaints and suspected Sjogren's syndrome (SjD).

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Burnout or Retire (4.12.2024)

Jack Cush, MD

Dr. Jack Cush reviews the news and journal reports from this past week on RheumNow.com. Is it time to worry about burnout and those who are leaving healthcare?

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ILD Onset in MDA-5 Dermatomyositis

Jack Cush, MD

Anti–melanoma differentiation-associated gene 5 (MDA5) antibody-positive dermatomyositis (DM) is a rare, aggressive and progressive subtype of DM.

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BSR Guideline on Management of Sjogren’s Syndrome Sjögren disease (SD) is the most common of all autoimmune disease, yet little is know of its etiology and there are insufficent interventions for those affected with mucosal or systemic manifestations. https://t.co/M5fQ8lyZBS https://t.co/30XpP3r4FV

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Dr. John Cush RheumNow ( View Tweet)
GPA Management in 2024 https://t.co/qTwI7oVMBI https://t.co/Tr0eVmcgNN

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Dr. John Cush RheumNow ( View Tweet)
#RNL2024 @RheumNow @philseo: I now give Tociliizumab for nearly all patients with GCA GiACTA shows we weren't doing well enough with steroid monotherapy GiACTA shows dosing frequency does not make a big difference in new diagnosis, but makes a difference in relapsing disease

Dr. John Cush RheumNow ( View Tweet)

#RNL2024 @anisha_dua Throwing the kitchen sink in severe GPA CYC + RTX combo - sick population (median GFR 9, 47% on HD, 52% DAH, all received PLEX too) - 85% survival, 69% not ESKD, low rates of relapse (13% at 36 mos) But, prolonged B cell depletion, aggressive Rx

Dr. John Cush RheumNow ( View Tweet)

The lateral foot/ankle anatomy 🥰 https://t.co/yuGt1seUd4

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Faraz Sethi farazzledphysio ( View Tweet)
Did you know the first clinical controlled trials were done on sailors with scurvy? They were randomized to: a quart of cider, HCl, 2 spoons of vinegar, pint of sea water, spicy nutmeg paste w/ water vs. 2 oranges and a lemon. Guess which sailors fared best? #RheumGR @UTSWRheum https://t.co/fAeCeIxZ9e

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TheDaoIndex KDAO2011 ( View Tweet)
PJP PPx in AAV @anisha_dua #RNL2024 @RheumNow 919 GPA pts on RTX - only 31% on TMP/SMX 13 pts devel PJP, not on PPx Overall decreased serious infections (HR 0.5), outpt infections HR 0.7 Adverse effects on TMP/SMX 29.6 vs 13.4 For every serious ifn avoided, 2-3 pts will have AE

Dr. John Cush RheumNow ( View Tweet)

Peripheral dermatomes & key muscles of the most important lumbosacral nerve roots. However, keep in mind that the muscles also receive contributions from other nerves (e.g., the extensor digitorum longus is innervated mainly by L5, but also from L4 and S1). https://t.co/auXMMddUIh

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Dr. OMID BANDARCHI OBandarchi ( View Tweet)
#peritendinous #ultrasoundguidedinjection with #osteniltendon for Tendinopathy of the #tibialisposterior #tendon #mskus #pocus #pocushub #GElogiqE10r3 https://t.co/8qe1G27tAl

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Dr Jörg Dünkel SportklinikBern ( View Tweet)
ICYMI: Vasculitis Pearls https://t.co/7z6b0Wj37X https://t.co/PHlOvFG9qQ

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Dr. John Cush RheumNow ( View Tweet)
ICYMI: Sex Disparities in PsA/SpA https://t.co/55zwjR8mNR https://t.co/fhhekNpHVA

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Dr. John Cush RheumNow ( View Tweet)
World Congress on OP, OA & MSK Disorders Bone and musculoskeletal disease researchers and physicians from around the world will meet today in London for the opening of the World Congress on Osteoporosis, Osteoarthritis and Musculoskeletal Diseases. https://t.co/kzvWD4Rmki https://t.co/PJQREsJO9v

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Dr. John Cush RheumNow ( View Tweet)
Join us 4/16 for Tuesday Night Rheumatology at 6:30pm ET. This week we'll be focusing on Vasculitis Mavens with: Vasculitis & Pregnancy - Catherine Sims, MD GPA Management in 2024 - Anisha Dua, MD, MPH Treat to Target in Vasculitis - Philip Seo, MD https://t.co/6IaCdCodGf https://t.co/HlZ8OiZWc4

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Dr. John Cush RheumNow ( View Tweet)
I’m seeing some “free market” simps defending Nature’s 12k open access fees. Guess it’s time to bring this back around. https://t.co/sPW2qHN5m8

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Dr. Glaucomflecken DGlaucomflecken ( View Tweet)
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