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Hydroxychloroquine: proposed risk factors for Retinopathy #EULAR2019 https://t.co/WkyNZ4GPVr
Dr Irwin Lim _connectedcare ( View Tweet)
Mease: SEAM study MTX vs Etanercept in PsA.
ETA effects > MTX with no additional benefit of combination.
But some MTX benefit (note no PBO arm).
Interesting separation between MTX<ETA for PASDAS (muli domain) but not DAPSA (joints only) #Eular2019 @RheumNow https://t.co/WSUlGE7NEf
Stefan Siebert StefanSiebert1 ( View Tweet)
#Gout patients tend not to tell doctors impact of gout on quality of life
👉🏼43% #mentalhealth
👉🏼27% impact on family
👉🏼26% relationship with partners
➡️🔟% lost job or retired due to gout
by Meulemeester #EULAR2019 https://t.co/fyrAyvpaYO
Dr Ai Lyn Tan DrAiLynTan ( View Tweet)
Mease: Filgotinib (selective JAK1i) in active PsA ph2. Promising data.
Interesting and informative way to present individual participant level data over time rather than just aggregate data - may be more useful for clinicians and patients to understand.
#EULAR2019 @RheumNow https://t.co/B0pLODWGJ9
Stefan Siebert StefanSiebert1 ( View Tweet)
So, what are we left with? Some patients get another year free of remission - that’s good. TCZ is steroid-sparing - that’s good. Still questions about longer follow-up and sequelae, and a year’s therapy doesn’t cure everyone. It’s not a panacea for all GCA ills, but it’s a start! https://t.co/6AiIQLnLFN
David Liew drdavidliew ( View Tweet)
Well it’s not all she wrote when flares come along, flares can be treated - some data on how to fix them, but beware the channeling bias https://t.co/o0rwYr1Ll7
David Liew drdavidliew ( View Tweet)
McInnes: Machine-learning separates out 13 clusters of PsA in RCT population (i.e. already selected).
Offers opportunities to reduce some of the massive heterogeneity in PsA to help inform biomarker studies and future precision medicine strategies. #Eular2019 @RheumNow https://t.co/h3Otp4Oq8U
Stefan Siebert StefanSiebert1 ( View Tweet)
For new knee inflammatory arthritis nearly 60% are in full remission at one year whereas 10% spread to progressive arthritis and 30% have persistent knee IA. Leiden Early arthritis cohort #EULAR2019 @RheumNow https://t.co/ZuLI1OCfhT https://t.co/x2Tr1tF0j6
Janet Pope Janetbirdope ( View Tweet)
Poster THU0687 FMF and schizo each increase mortality and worse if co-occurrence #EULAR2019 @RheumNow https://t.co/nVfiw25Lzf https://t.co/U9KELLJzVD
Janet Pope Janetbirdope ( View Tweet)
Be sure not to miss our symposium tomorrow morning: ‘The Patient Perspective: Addressing Challenges Facing Women with #axSpA and PsA’. Join us tomorrow! #EULAR2019 #psoriaticarthritis https://t.co/G0NkmblAhI
UCB News ucb_news ( View Tweet)
Checkpoint inhibitor use is exploding in cancer Rx. Big data review of 13000 cases of immune mediated reactions are mostly endo, GI and pulmonary and NOT rheumatic THUS0628 #EULAR2019 @RheumNow https://t.co/iYO8t6ALBx
Janet Pope Janetbirdope ( View Tweet)
Olofsson, Sweden: important topic of unacceptable residual pain despite biologic in PsA with >80% of this pain despite good inflammatory control
#Eular2019 @RheumNow https://t.co/vjiakjCKR0
Stefan Siebert StefanSiebert1 ( View Tweet)
What happens to momo or bilateral knee synovitis in 12 months? #EULAR2019 @RheumNow THU0674
Janet Pope Janetbirdope ( View Tweet)
Strange lack of association Schizophrenia is decreased in Familial Med fever (FMF). HLA B08 is protective against schizo in RA. They speculate that pure autoimmune diseases have more schizo and auto inflammatory less schizo #EULAR2019 @RheumNow
Janet Pope Janetbirdope ( View Tweet)
Great clinical advice from @MarieKostine in today's EULAR recommendations on rheumatic irAEs from cancer immunotherapy, but most of all, oncologists should be encouraged to refer promptly and rheumatologists need to make themselves readily accessible! #EULAR2019 OP0165 @RheumNow
David Liew drdavidliew ( View Tweet)
Immune mediated reactions from checkpoint inhibitors mostly are rheumatologic. THU0628 #EULAR2019 @RheumNow
Janet Pope Janetbirdope ( View Tweet)
Come see our poster THU0689- asthma and elevation of ACPA prior to RA onset. Women with asthma had 4-fold increased risk pre-RA ACPA+ a mean of 8 years prior to RA dx. Supports mucosal hypothesis where inflamed airways promote ACPA genesis #EULAR19 https://t.co/zivVinwEWS
Jeff Sparks jeffsparks ( View Tweet)
Giant cell arteritis 42% with clinical remission and no treatment after 1 year of weekly #Tocilizumab... remission after 2 years.. Dr. John H. Stone https://t.co/WqvGLxBLQA
Dr.Martínez MtzReuma ( View Tweet)
ANCA #VASCULITIS
👉🏻A maintenance treatment should be prescribed
👉🏻Anti-PR3 patients > MPO
👉🏻Rituximab is the best drug to maintain remission
👉🏻Some patients could deserve a"very long term maintenance treatment",may be all life
👉🏻A specific approach is needed in EGPA
#EULAR2019 https://t.co/s3JlUahN4m
Juan Ovalles, MD, PhD DrJuanOvalles ( View Tweet)
Flares: well, I had hoped for more from that top highlighted line. What is going to happen to our real-life patients who have had a year of TCZ and then come off? https://t.co/QvsEfYpahi
David Liew drdavidliew ( View Tweet)