All News
Matters of the heart: cardiovascular disease and mortality in RA
Two large retrospective cohort studies presented by the team at Mayo Clinic, Rochester MN examine the burden of stroke, as well as overall and cause-specific mortality in people with RA (POS0591 and POS0592).
Read Article
Look out for multimorbidity in rheumatoid arthritis. McInnes I #EULAR2024 @RheumNow https://t.co/kgshkNcyLn
Dr. Antoni Chan synovialjoints ( View Tweet)
#EULAR2024 Please find our Day 1 & Day 2 Recap of selective abstracts/research presented at the conference 😃@RheumNow @DrMiniDey
https://t.co/AHl18gS7gF https://t.co/LEoa9rBNly
Links:
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
#EULAR2024 OP0295 Approriate patient stratification matters in trials. H2H RCT of Tocilizumab vs Rituximab in refractory #SSc-ILD (failed CyC), stratified based on RNA-seq of lungs biopsy showed improved efficacy in TCZ with low B-cell lineage expression signature @RheumNow https://t.co/7ME3Bd2PeM
Links:
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
Infrapatellar fat pad morphology- mainly volume on MRI associated progostication in knee #OA - structural changes!
using OAI data #EULAR2024 abst#OP0292 @rheumnow
Bella Mehta bella_mehta ( View Tweet)
OP0162 looks at mortality in 21277 seropositive and seronegative #RA
5-year mortality risk in both groups decreased over time but is higher in seropositive vs negative
Sex-specific analysis reveals serological status in women did not affect mortality risk
@RheumNow #EULAR2024
Mrinalini Dey DrMiniDey ( View Tweet)
#EULAR2024 OP0288 Patients with Scleroderma shouldn’t be excluded from Lung Transplantation because of a concern with post-surgery complications/long term complications. Data from Italy of N=13 pts showed 93% survival, improved disesase activity & FVC over 2 years @RheumNow https://t.co/zPFB1MFxdc
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
➡️OP0127- Can we predict who will get persistently active disease in people with palindromic rheumatism (PR)?
📊Cohort of 161 PR
❗️Predictive factors: Female gender, CCP, RF, >40yo, smoking & interval between flares of <1m ➡️ may be used to risk stratify
@RheumNow #EULAR2024
Mrinalini Dey DrMiniDey ( View Tweet)
beautiful work Univ of Qld - rat SpA model bacterial dna into entheses blocked by 23i not 17i @RheumNow #EULAR2024 https://t.co/X9hzkA56d0
Peter Nash drpnash ( View Tweet)
Différent stages of RA with disease progression. McInnes M #EULAR2024 @RheumNow https://t.co/iKpggGYU0k
Dr. Antoni Chan synovialjoints ( View Tweet)
#EULAR2024 OP0256 Phase 2 RCT ReSScue data of fecal microbiota transplantation did not meet primary endpoint (bloating & diarrhoea) in scleroderma. How about impact on faecal incontinence symptoms? This improved throughout 20wks. Could be due improved stool consistency @RheumNow https://t.co/1t7d3M5S4Z
Links:
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
The fracture risk with glucocorticoids is dose dependent. Lems W #EULAR2024 @RheumNow https://t.co/TGjKu1vfXx
Dr. Antoni Chan synovialjoints ( View Tweet)
#EULAR2024 POS0257 One for the future. Phase 2A RCT showed KPG-818, a Novel Cereblon Modulator (targets Aiolos & Ikaros) was well tolerated with
efficacy signal (SLEDAI-2K & CLASI-50). Effect and safety profile were numerically better in the lowest dose @RheumNow https://t.co/Bjk9zBRmVo
Md Yuzaiful Md Yusof Yuz6Yusof ( View Tweet)
PsA: one composite index that does it all
cDAPSA + Investigator’s Global Assessment (IGA) of PSO
Cohen’s kappa 0.72 & 88% concordance with PASDAS LDA
88% sensitivity & specificity in DISCOVER-1 & 2 trial data
#EULAR2024 @RheumNow POS0254 https://t.co/ZBb1M4IusC
Aurelie Najm AurelieRheumo ( View Tweet)
🚨 New 68Ga-FAPI-04-PET/CT, fibroblast activation tracer
38 PSO patients w/ arthralgia
Correlation PET/CT SUVmax, TJC & tender enthesis count
68Ga-FAPI-04 uptake = higher risk developing PsA 6mo
Shows signs of inflammation before MSUS!
#EULAR2024 @RheumNow POS0242 https://t.co/GG6qeD4qJn
Aurelie Najm AurelieRheumo ( View Tweet)
Leflunomide for #PMR?
✅ #Leflunomide FAR more effective than #MTX in #polymyalgia #rheumatica
V fast withdrawal of #prednisone
#LEF ~4 to 5 months
#MTX 30 mos!
⬇️flares w LEF
😮
#EULAR2024 @RheumNow @eular_org
@SebaUltraTrail https://t.co/2hk0yMH6gY
Links:
Janet Pope Janetbirdope ( View Tweet)
Some of these drugs dont seem to work in all of knee OA. I guess its really difficult to tease out different subtypes.
Subgroup analysis from a Phase 3 intraarticular JTA-004 injection at #EULAR2024 abst#Op0305 @RheumNow https://t.co/jbkLYyl93e
Links:
Bella Mehta bella_mehta ( View Tweet)
🧠POS0730 Self-reported cognitive function in older adults with #SLE in @ndb_org registry
➡️Cognitive symptoms significantly worse in older people w SLE vs other #RMDs
➡️Perceptions of cognitive function assoc with less satisfaction with health & ⬇️ #QoL
@RheumNow #EULAR2024
Mrinalini Dey DrMiniDey ( View Tweet)
Check point inhibitors may cause bone loss and fractures. Lems W #EULAR2024 @RheumNow https://t.co/rf1AU60Eah
Dr. Antoni Chan synovialjoints ( View Tweet)
This can be coming to a clinic near you. Hotspot/ROI ratio (HRR) values from high-resolution thermographic marker in the detection of joint inflammation, compared to joint ultrasound showed excellent performance in the differentiation of joints with US inflammatory activity from… https://t.co/1unRxxgHAd https://t.co/tOPDSxzvwB
Links:
Dr. Antoni Chan synovialjoints ( View Tweet)