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Ixekizumab and Complete Resolution of Enthesitis and Dactylitis

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d Jack Cush, MD

Jan 30, 2019

IL-17 inhibitors have proven to be effective in psoriatic arthritis. Analyses of ixekizumab-treated PsA patients with enthesitis or dactylitis shows this approach to yield significant improvements in enthesitis and dactylitis.

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Vertebroplasty and Kyphoplasty Shown to Be Ineffective

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d Jack Cush, MD

Jan 29, 2019

There are approximately 750,000 new vertebral compression fractures each year in the United States, with resultant acute and chronic back pain in over one‐third of patients with vertebral fractures (VF). Both percutaneous vertebroplasty or balloon kyphoplasty have been advocated as useful m

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Multidisciplinary Recommendations for Rheumatoid Foot Problems

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d Jack Cush, MD

Jan 28, 2019

Approximately 90% of patients with rheumatoid arthritis (RA) have foot problems.

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Improved Survival with Renal Transplant in SLE

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d Jack Cush, MD

Jan 28, 2019

The Annals of Internal Medicine has published a cohort study of lupus nephritis patients with end-stage renal disease showing that renal transplantation is associated with improved survival benefit, and a reduction in death from cardiovascular disease and infection.

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RheumNow Podcast – TNFs and the Inflammasome (1.25.19)

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d Jack Cush, MD

Jan 25, 2019

Dr Jack Cush reviews the news from the past week at RheumNow.com.

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UK pts w/ hemochromatosis homozygous for HFE p.C282Y finds men 40-70 w/ incr risk of Hemochr Dx, (OR 411), liver Dz (4.3), RA (2.23), OA (2.01) & DM (1.53). Heterozygotes w/ hemochromatosis was more common but morbidity was modest. https://t.co/8NyRRJGqTl

Links:

https://buff.ly/2VWCMx3

Dr. John Cush RheumNow ( View Tweet)

Jan 30, 2019

Using data mining and machine learning of medical/facility claims the estimated prevalence of myalgic encephalomyelitis (ME) or chronic fatigue syndrome (CFS) in the U.S. is 1.7 million to 3.38 million - with 35-40% of patients being MEN. https://t.co/mXy7sQEPgb

Links:

https://buff.ly/2UjAer5

Dr. John Cush RheumNow ( View Tweet)

Jan 30, 2019

Congratulations to Dr. Sasha Bernatsky for receiving the Arthritis Alliance of Canada Award https://t.co/vgiKcTXuNK

Links:

https://buff.ly/2Se8SoQ

Dr. John Cush RheumNow ( View Tweet)

Jan 29, 2019

QD Clinic - The Tophi Guy | Gout case management from https://t.co/2dcFVgu8z6 https://t.co/Nj3PbgVuFK

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Dr. John Cush RheumNow ( View Tweet)

Jan 29, 2019

Comparison of 187 RA and 157 without inflammatory joint dz, shows a significant association between periodontitis and RA (adjusted OR = 20.57). Periodontitis severity was significantly associated with RA disease activity (p < 0.001) https://t.co/Bmv2LKRnYz

Links:

https://buff.ly/2CDZEbU

Dr. John Cush RheumNow ( View Tweet)

Jan 29, 2019

2014-2015 study of 750K from Southern Sweden shows 24% of OA patients used opioids (2 fold higher than those without knee or hip OA).

Dr. John Cush RheumNow ( View Tweet)

Jan 29, 2019

QD Clinic - RA patients on Biologic with Recurrent UTI. Lessons from the clinic and J Cush, MD https://t.co/OaFY6GCT80 via @YouTube

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https://buff.ly/2RlnP48

Dr. John Cush RheumNow ( View Tweet)

Jan 28, 2019

101 kids w/ Takayasus finds 3% mortality in Yr 1, 50% morbidity in 5 yrs. Median onset was 14 yrs, 76%F. Sxs include HTN (70%), BP discrep(55%), bruits (52%), pulse deficits (38%). Artery Inv: Renal (62%), aorta (43%), subclavian (44%), carotid (43%). https://t.co/nXdjLviRyk

Links:

https://buff.ly/2DE0Uxc

Dr. John Cush RheumNow ( View Tweet)

Jan 28, 2019

Metanalysis of 38 RCTs & 19 agents shows greater DEXA improvements assoc w/ greater reductions in vertebral & hip Fx risk. A 2% to 6% incr in total hip BMD--> expect 28%-66% reduced vert Fx risk. 2%-6% incr in hip BMD--> expect 16%-40% lower hip Fx risk https://t.co/ceY5X31xXh

Links:

https://buff.ly/2sRN1W5

Dr. John Cush RheumNow ( View Tweet)

Jan 28, 2019

The QD Clinic Podcast - Week 3. a compilation of short videos from RheumNow and Dr. Cush Listent on iTunes or here https://t.co/h8lnejvHe5

Links:

https://buff.ly/2G1fSiu

Dr. John Cush RheumNow ( View Tweet)

Jan 28, 2019

QD Clinic - A Different Kind of Visit | by Jack Cush https://t.co/Ryr45iWCum

Links:

https://buff.ly/2Wnw2s7

Dr. John Cush RheumNow ( View Tweet)

Jan 27, 2019

QD - Hemoptysis with lupus: Stable lupus patient suddenly complains of hemoptysis - whats the differential diagnosis? Lessons and cases from the Rheumatology clinic. https://t.co/fagvh3TpVm #lupus

Links:

https://buff.ly/2RT7MiX

Dr. John Cush RheumNow ( View Tweet)

Jan 25, 2019

Using the 1998-2014 U.S. National Inpatient Sample- gout was associated with 9-20% higher healthcare utilization and 6% higher hazard of transfusion after primary hip replacement surgery. https://t.co/cSFnVJiX8s

Links:

https://buff.ly/2U8wvwu

Dr. John Cush RheumNow ( View Tweet)

Jan 25, 2019

QD lessons from the Clinic - The "No Show" patient | RheumNow - https://t.co/olslXtzmvZ

Links:

https://buff.ly/2CFtmgu

Dr. John Cush RheumNow ( View Tweet)

Jan 24, 2019

Meta-analysis of 4719 elderly RA/IBD/PSO pts on biologics vs 13,305 younger vs 3961 older patients (no biologics) shows biologic use in elderly to be assoc w/ an increased risk of infections (3.6 fold increase in risk) but no increase in cancer or death https://t.co/pWtMMo2KQ1

Links:

https://buff.ly/2RLAbYd

Dr. John Cush RheumNow ( View Tweet)

Jan 24, 2019

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