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NEJM Review - Glucocorticoid-Induced Osteoporosis

d Jack Cush, MD

Lenore Buckley and Mary Humphrey have published a nice review of glucocorticoid-induced osteoporosis (GIOP) in the NEJM.

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Price of Drug Promotion Skyrockets

d Jack Cush, MD

JAMA reports that health care advertising costs in the U.S. have almost doubled over the past two decades, surging from $17.7 billion in 1997 to at least $29.9 billion in 2016.

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Combo RA Treatment May Boost Risk for Serious Adverse Events

d RheumNow

A current meta-analysis of safety and efficacy of combination bDMARD treatment in RA patients shows that combination treatments increase serious advese event (SAE) risks, and the risk for serious infections in particular.

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Opioids Double Rates of Suicides and Overdoses

d Jack Cush, MD

An article in the New England Journal of Medicine reports that the rates of suicide and drug overdoses has doubled in the last 17 years, and that opioids are largely to blame.

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BMS Buyout of Celgene for $74 Billion

d Jack Cush, MD

Reuters reports that Bristol-Myers Squibb (BMS) has announced its intention to buy Celgene Corp for nearly $74 billion in a cash-and-stock deal.

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Tuhina Neogi, MD, PhD, professor of medicine, has been named chief of the section of rheumatology, in the department of medicine at BU School of Medicine (BUSM) and Boston Medical Center (BMC). https://t.co/0HUj0ji40o

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Dr. John Cush RheumNow ( View Tweet)

FDA has approved a single-injection hyaluronic acid (Durolane – Bioventus) and an ER formulation of the synthetic corticosteroid triamcinolone acetonide (Zilretta – Flexion) for intra-articular (IA) treatment of osteoarthritic knee pain. https://t.co/7rgsflNMVq

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Dr. John Cush RheumNow ( View Tweet)

Cluster analysis of 157 SAPHO pts shows 3 distinct patterns or types - spinal type (44.6%; spinal, sacral); costal type (33.1%; ribs) and sternoclavicular type (22.3%) disease course was longer in SC type than costal or spinal types (P < 0.001). https://t.co/NI7AylAoZt

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Dr. John Cush RheumNow ( View Tweet)

QD Video from RheumNow - these are daily lessons from the arthritis clinic. Here Dr. Cush discusses what to call seronegative inflammatory arthritis. https://t.co/f7LlwUU0aq

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Dr. John Cush RheumNow ( View Tweet)

QD Video from RheumNow - Dicusssion of statins and myalgias/arthralgias. https://t.co/zKFZEF6MiL

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Dr. John Cush RheumNow ( View Tweet)

Medicare claims analysis shows that older ankylosing spondylitis patients have a 2 fold increased risk of THAT and TKA (R R 2.14, 95% CI 1.93–2.38). https://t.co/HVFFQNTmdz

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Dr. John Cush RheumNow ( View Tweet)

Obesity makes everything worse, including SLE! Study of 148 SLE pts; the 32% who were obese had worse disease activity, depression, pain and fatigue. https://t.co/PQOQrBca2a

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Dr. John Cush RheumNow ( View Tweet)

Rheumatology Year in Review - New Drugs, irAEs, Enbrel in court, Opioids, new JAKs, Hot PsA Trial, new Lupus drugs, Medical Marijuana, Expen$ive Rheum drugs, Senolytics. https://t.co/9VpM4yRGfY

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Dr. John Cush RheumNow ( View Tweet)

RheumNow Weekly Podcast is up - watch here: https://t.co/vAtEYSPIhG or listen on iTunes or here https://t.co/D3n7so7mN9

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Dr. John Cush RheumNow ( View Tweet)

Potential Blockbuster Takeover - BMS proposal to takeover Celgene for $74 Billion! Bristol-Myers' acquisition of Celgene would rank among the industry's largest ever. https://t.co/hWuygShcNq

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Dr. John Cush RheumNow ( View Tweet)

Learn about the pathophysiology, assessment & treatment of #psoriatic #dactylitis in our new #Perspectives article Now online at https://t.co/ewqx3xdXTz #PsoriaticArthritis #Arthritis #Enthesitis https://t.co/2bkHgKNGPQ

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NatRevRheumatol NatRevRheumatol ( View Tweet)
Happy birthday to the US Public Health Service Commissioned Corps. I’m proud of my colleagues who continue the Commissioned Corps’ 130-year legacy as the frontline defender of public health, providing critical health expertise and rapid response to public health emergencies.

Secretary Alex Azar SecAzar ( View Tweet)

2018 Rheumatology Year In Review | RheumNow - Rheumatology News & Information https://t.co/zo1AaWZ0MR

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Dr. John Cush RheumNow ( View Tweet)

FDA warns fluoroquinolone use may increase risk ofruptures or tears in the aorta. Thus Fluoroquinolones should not be used w/ aortic aneurysms, peripheral vascular Dz, HTN, Marfans/Ehlers-Danlos, or the elderly, unless there are no other options available https://t.co/aTEE0keIS8

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Dr. John Cush RheumNow ( View Tweet)

Finnish followup study of 68,800 hip fracture pts w hip surgery finds 4.6% w/ complications - esp with heavy alcoholism (HR 1.38); Parkinson’s (1.22); osteoarthritis (2.02); rheumatic Dz (1.44); those w/ depression/psychosis, operative delay, prior THR https://t.co/StahnHXRuZ

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Dr. John Cush RheumNow ( View Tweet)

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