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Proposed investigations (findings) in the diagnosis of Stills disease: - CRP, ESR, Ferritin (high) - W/U for infection, cancer (negative) - Serologies (negative) - consider Imaging (CXR, CT, US, PET) https://t.co/l3yqAx6PA0 https://t.co/Sg7okwKHaw

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Dr. John Cush RheumNow ( View Tweet)
GRAPPA,PsA,guideline

New Updated GRAPPA Psoriatic Arthritis Recommendations

d Jack Cush, MD

The GRAPPA (Group for Research and Assessment of Psoriasis and Psoriatic Arthritis) treatment recommendations have been updated and the 2021 evidence-based guidance is rich in treatment recommendations based on the key disease "domains" - peripheral arthritis, axial disease, enthesitis, dactylitis, skin and nail psoriasis; with new PsA related domains uveitis and inflammatory bowel disease.

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Yes No

Can we stop RA before it happens?

d David Liew, FRACP

Rheumatologists have long hoped and wondered whether the right type of early intervention could prevent rheumatoid arthritis occurring in at-risk individuals.

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Gender

Time to consider gender stratification in AxSpA diagnosis and management

d Aurelie Najm, MD, PhD

Differences across genders in many aspects related to rheumatic diseases diagnosis, phenotyping, trajectories definition and prediction of response to treatment have been overlooked.

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ice cubes

Topical therapies take centre stage

d Richard Conway, MBBChBAO, PhD

Topical treatments have so often been the low level “sure you can try this” option. However there are exciting data that these approaches may become part of our main armamentarium. 

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Sex differences in axSpA: we’re continuing to better understand the differences in imaging findings. Existing MRI scoring may underserve axSpA in women. Added to therapy differences, a lot to readdress for our female axSpA patients. from roundup #EULAR2022 @RheumNow https://t.co/8wCKx9AFcM
David Liew drdavidliew ( View Tweet)
EULAR,poster

EULAR 2022 – Day 3 Report

d Jack Cush, MD

By now, those of us attending the meeting know how to find a free coffee or sprite, have found comfortable meeting nooks and know our way around! PAnd congrats to you virtual Rheums for mastering the multi-screen, multitask simultaneous consumption posters, tweets and oral abstract presentations.

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Mease et al. Minimal radiographic progression in patients treated with IL-23i guselkumab over 2 years. This trial enriched for high-risk radiographic progression. Clinical response associated with less radiographic progression. @RheumNow #EULAR2022 POS1035 https://t.co/1C21MNVpV8
Richard Conway RichardPAConway ( View Tweet)
52 wk trial using MSK Ultrasound study on PsA receiving secukinumab showed an early and continued improvement in GLOESS scores. Synovial hypertrophy most responsive. Hands and feet, wrist and knees most affected and responsive. @RheumNow #EULAR2022 ABST#OP0260 https://t.co/jeQezIWLxa
Robert B Chao, MD doctorRBC ( View Tweet)
#EULAR2022 POS0276 Xray & US for CPPD: US: sensitivity in all sites Xray: highly specific, low sensitivity Combo: Best for patients with Negative Xray or Inconclusive US (only one positive site) @Rheumnow @MymaAlbaydaMD @USSONAR_Rh

Eric Dein ericdeinmd ( View Tweet)

Deep learning can be used to distinguish seropositive RA from seronegative RA and PsA based on MRI. Early changes in PsO may suggest a PsA-like MRI pattern may be present! Is this how we predict which PsO -> PsA? @RheumNow #EULAR2022 ABST#OP0292 https://t.co/NGfFkSqlaM
Robert B Chao, MD doctorRBC ( View Tweet)
#EULAR2022 POS0278: Proof of concept US study: 💎CPP crystals do NOT generate posterior shadowing 💎MSU and hydroxyapatite did have shadowing, proportional to concentration of crystals @Rheumnow @MymaAlbaydaMD @USSONAR_Rh

Eric Dein ericdeinmd ( View Tweet)

There's nothing like a good physical examination Temporal artery exam & ultrasound vs temporal artery biopsy n=97 consecutive ?GCA pts from Carlo Salvarini's group Very decent PPV Those TA exam findings can be hard to find, but they're gold dust. POS0820 #EULAR2022 @RheumNow https://t.co/X9TzIqQBaB
David Liew drdavidliew ( View Tweet)
Puzzle pieces

Polymyalgia rheumatica immunological puzzle further illustrated

d David Liew, FRACP

Infiltrating macrophages expressing IL-6 and GM-CSF may drive the subacromial bursitis often seen in polymyalgia rheumatica, according to new research (abstract OP0015) prese

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What is "backfill" on MRI? Answer: joint space lesions with a calcified matrix resembling new bone formation found in axSpA. #EULAR2022 POS0149 argues for a standardization of this nomenclature. @RheumNow https://t.co/ifrowQnRcn
Dr. Rachel Tate uptoTate ( View Tweet)
To contrast or not to contrast (in RA hand MRI?) POS0718 from #EULAR2022 showed good correlation between contrast/non-contrast imaging in synovitis, less so in tenosynovitis however. https://t.co/xL4XcRlIog @RheumNow https://t.co/0cTep6MHLu

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Dr. Rachel Tate uptoTate ( View Tweet)
Differentiating AS from OCI using CT scanning by Terrier et al showed that Subchondral Bone Attenuation Coefficient (SBAC) was higher in OCI than AS with a threshold of >7500 Hounslow Units discriminating the two conditions #EULAR2022 @RheumNow POS0126 https://t.co/8MdSe3Dqp7
Dr. Antoni Chan synovialjoints ( View Tweet)
#EULAR2022 Ultrasound may be used to evaluate patients with RA (POS1393) and SSc (POS1394) 👁️Look for B-lines and pleural irregularity Will require training of MSKUS rheumatologists, but another potential application of US in clinical practice @RheumNow @MymaAlbaydaMD @USSONAR_Rh https://t.co/qtnBviKA3w
Eric Dein ericdeinmd ( View Tweet)
The PROOF study showed the predictors of radiographic progression included male gender HR 3.16, good response to NSAIDs HR 4.66, fulfillment of the imaging arm HR 6.64 and HLA-B27+ HR 3.99 by Poddubnyy et al #EULAR2022 @RheumNow OP0149

Dr. Antoni Chan synovialjoints ( View Tweet)

Dermatologists doing ultrasound (US) for earlier diagnosis of PsA? Grobelski et al showed in this study of 140 PsA patients, pre-US sensitivity/specifity was 81%/55%, post-US this changed to 62%/91%. Targeted US improved accuracy of referrals for PsA #EULAR2022 @RheumNow OP0029 https://t.co/iajqMuPqcd
Dr. Antoni Chan synovialjoints ( View Tweet)

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