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RheumNow Podcast - RWCS 2022 Roundup (2.19.2022)

Jack Cush, MD

Drs. Jack Cush and Artie Kavanaugh review the highlights of the RWCS (Rheumatology Winter Clinical Symposium) from Maui.


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RA Hands Difficult deformity

BMI Most Impairs Treatment Response in Rheumatoid Arthritis

Jack Cush, MD

Using a large cohort of rheumatoid arthritis (RA) patients, Tumor-Necrosis Factor inhibitors (TNFi) were compared to non-TNFi biologic therapies and showed that poorer responses were seen in obese and underweight patients, with no clear superiority of non-TNFi therapy over TNFi therapy in an

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Rheumatoid Arthritis Nonadherence is Multifactorial

Jack Cush, MD

The consequences of medication non-adherence (NA) in rheumatoid arthritis (RA) care are numerous and damaging.  A 6-month prospective cohort study of RA patients shows NA to vary according to drug type and be related to psychological, communicational, logistic, sociodemographic or clini

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ACR Updates Clinical Guidance for Multisystem Inflammatory Syndrome in Children Associated With COVID

Jack Cush, MD

A Task Force from the ACR has provided an updated (version 3) guidance for the diagnosis and management of Multisystem Inflammatory Syndrome in Children (MIS-C), a COVID related condition characterized by fever, inflammation, and multiorgan dysfunction.

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Vitamin D and the Risk of Autoimmune Diseases

Jack Cush, MD

The results of the VITAL study (presented at ACR 2021) are now published by BMJ, showing that vitamin D and omega 3 fatty acids reduce the overall risk of autoimmune disease (AID) in a population based intervention trial.

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Methotrexate Side Effects

Jack Cush, MD

Data came from the UK Rheumatoid Arthritis Medication Study (RAMS), a prospective cohort of early RA patients starting methotrexate (MTX) shows that in the first year, adverse events (AE) were common, but not serious.

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An Ounce of Prevention (2.4.2022)

Jack Cush, MD

Dr. Jack Cush reviews the news and journal reports from this past week on RheumNow.com.  He discusses the GI side effects of IL-17 inhibitors, downstream revenues from rheumatology care and dietary prevention of gout. 

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Pediatric Rheumatology Workforce Shortages

Jack Cush, MD

Two recent analyses from the USA and Canada point to a significant unmet need with regard to pediatric rheumatologists.

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Watch: Treat to Target Strategy in RA: Dr. Dylan Lee at RWCS22 https://t.co/QExalESU2q https://t.co/cqzL4FYOUl

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Dr. John Cush RheumNow ( View Tweet)
ICYMI: Voriconazole-induced synovitis, enthesitis and periostitis described in woman treated for invasive aspergillosis. She had polyarthralgias, synovitis, and periostitis on xray. Voriconazole prev. caused periostitis; now drug induced arthritis? https://t.co/6HfLGIaEsU

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Dr. John Cush RheumNow ( View Tweet)

NAFLD is increased in #RA. Risk factors include male, BMI, MTX dose, inflammation. @UmaMahadevanIBD @RWCSmtg #rwcs https://t.co/V94aaO5vEH
Dr. John Cush RheumNow ( View Tweet)
Doximity ranked 15 specialties w/ high telehealth adoption rates 1 Endocrinology 2 GI 3. Rheumatology 4 GU 5 Nephrology 6 Cardiology 7 ENT 8 Neuro 9 Allergy 10 Heme/Onc 11Family medicine 12 Dermatology 13 Geriatrics 14 Pulm 15 Psych https://t.co/d7xm1ovk15

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Dr. John Cush RheumNow ( View Tweet)

NOR-DRUM study shows that TDM, therapeutic drug monitoring, is beneficial. Study of RA, PSA, AS, Crohn's, UC Rheums don't do this, should they? #RWCS2022 @RWCSmtg https://t.co/Dc6mgr5jrL
Dr. John Cush RheumNow ( View Tweet)
Rheumatoid Arthritis Nonadherence is Multifactorial A 6-month prospective cohort study of RA patients shows NA to vary according to drug type and be related to psychological, communicational, logistic, sociodemographic or clinical factors. https://t.co/FWamPS2fTQ https://t.co/EtoStfdTsI

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Dr. John Cush RheumNow ( View Tweet)
Fatigue in Early RA registry - study of n = 1236 pts w/ Dz duration 11 mos. The prevalence rates of fatigue was 44% and severe fatigue 19% and was stable over 3 yrs. Greater fatigue in women, high pain, mental Dz, function; BUT NOT SJC or ESR https://t.co/hEgPbsAqYZ

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Dr. John Cush RheumNow ( View Tweet)

CARRA Registry looked at TNFi use in JIA and found a nearly 3 fold increased risk of psoriasis. 8225 pts w/ 3.9 yrs of F/U. 54% recv TNFi; the aHR of new onset of psoriasis after TNFi exposure was 2.93 (2.15 to 3.98). MTX had lower risk (HR 0.45) https://t.co/Z6qvlS26M9

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Dr. John Cush RheumNow ( View Tweet)

Analysis of nearly 1000 undifferentiated-arthritis(UA) pts show that MRI use is most effective when applied to those who are seronegative or who have oligoathritis. https://t.co/aKIp2rZSNk

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Dr. John Cush RheumNow ( View Tweet)

Prevalence of PsA, axSpA & RA (2017) in Norwegian adults is 0.46%, 0.41%, & 0.78%. In 2017, 27.3% of RA patients, 25.7% of PsA patients and 35.1% of axSpA patients used biologic DMARDs (biologics more freq in youngers; infrequent if ≥55 yrs https://t.co/oqlpPmam6R

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Dr. John Cush RheumNow ( View Tweet)

Finnish Parkinson’s disease (FINPARK) cohort (22,189) looked at the assoc w/ #RA. RA pts using only chloroquine/hydroxychloroquine was associated with a lower risk of developing PD (adjusted OR 0.74); not with other DMARDs https://t.co/yZhgVT0xLh

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Dr. John Cush RheumNow ( View Tweet)

We are excited to announce that Dr. Ernest Choy will be joining us at RheumNow Live, leading a presentation on Precision Medicine in Rheumatoid Arthritis. Join the discussion on March 19-20. Invigorate, Instigate and Debate Rheumatology at #RNL2022 https://t.co/4uXQfRvRgc https://t.co/7KcPXadGcY

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Dr. John Cush RheumNow ( View Tweet)
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