All News
FDA Authorizes 2nd Booster for Older and Immunocompromised Individuals
FDA
Today, the U.S. Food and Drug Administration authorized a second booster dose of either the Pfizer-BioNTech or the Moderna COVID-19 vaccines for older people and certain immunocompromised individuals.
Read Article
Lupus Worries (3-25-22)
Dr. Jack Cush Reviews the news and journal reports from the past week in RheumNow.com.
Read Article
Stable Low Risk of Acute Coronary Syndrome in RA
A Nordic multinational collaborative study examined the risk of acute coronary syndrome (ACS) in rheumatoid arthritis and found a less than 2 fold increased risk of ACS patients initiating biologic disease-modifying antirheumatic drugs (bDMARDs) with little risk variation with short-ter
Read Article
Your Rheumatoid Questions from RNL 2022
Rheumatologists questions for Dr. Jack Cush QD
Clinic is sponsored by RheumNow's PsA All the Way Campaign in April 2022
https://t.co/sHBMKNvoXQ https://t.co/jcQgOIz7xt
Links:
Dr. John Cush RheumNow ( View Tweet)
Free Teaching PDF on "What is Rheumatoid Arthritis" from JAMA https://t.co/EGdq1jbjzJ
Links:
Dr. John Cush RheumNow ( View Tweet)
Adipokines are associated with CHF hospitalization (HR 1.39) & CVD-related death (HR 1.49) in #RA pts, especially in non-obese RA. This includes High leptin assoc w/ CV-death (HR 1.44) and High FGF-21 w/ lower CAD (HR 0.75) https://t.co/GQx1kzFOIJ https://t.co/M6MF73xPYs
Links:
Dr. John Cush RheumNow ( View Tweet)
ICYMI: Environmental Pollutants Ups Autoimmune Disease Risk
An Italian environmental study shows that air pollution increases the risk of autoimmune diseases, in particular rheumatoid arthritis, CTDs and inflammatory bowel diseases (IBD).
https://t.co/oKdgSZ2jAF https://t.co/WI7aShKR97
Links:
Dr. John Cush RheumNow ( View Tweet)
ICYMI: Drugs for Pregnancy Hopefuls
A Young Woman has uncontrolled RA, but wants to get pregnant.
What do you chose?
https://t.co/Sunx8RWRfM https://t.co/hsFNhVfwHd
Links:
Dr. John Cush RheumNow ( View Tweet)
High disease trajectory despite disease control (^HAQ > DAS28) in RA is more likely with higher pain, fatigue & depression. 10 ys study of 2500 RA pts from NOAR, ESPOIR, ERAN) https://t.co/mrB7fog6PD https://t.co/tqm3LPkOdM
Links:
Dr. John Cush RheumNow ( View Tweet)
Having the MUC5B promoter variant increases odds of RA-ILD w/ earlier onset in RA, esp w/ older age of RA onset. Mass Gen Biobank study of 1,005 RA pts; MUC5B found in 15% w/ incr risk of RA-ILD (OR 3.34) & RA onset after 55 yrs (OR 1.52) https://t.co/5odVWnpuxo https://t.co/zeKxADTSBZ
Links:
Dr. John Cush RheumNow ( View Tweet)
Aging & Inflammatory Rheumatic Dis is a growing Problem:
- Multimorbidity drives polypharmacy & compounds safety risks
- More malnutrition, sarcopenia & frailty
- Phenotype of Rheum Dz changes w/ age
- Tx differs for the elderly
- Elder RA is undertreated https://t.co/J2q0mEOqDd https://t.co/VfolGeYx6V
Dr. John Cush RheumNow ( View Tweet)
Phases preceding RA diagnosis.
@karen_kc123 @RheumNow #RNL2022 https://t.co/KJT9ml8ZJY
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
Completed early RA prevention trial!
One dose of Rituximab at day zero in the PRAIRI Trial, delayed onset of RA diagnosis.
After 36 months mo difference .
@karen_kc123 @RheumNow #RNL2022 https://t.co/R3639V6b07
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
Patient-centered, holistic approach in #multimorbidity management.
🔑 Patients with #RA and #MM need help and coaching in guiding and directing their care.
🔑 Good communication with healthcare provider is the key.
@RheumNow #RNL2022 https://t.co/iLrZAT0y9r
Elena MyasoedovaMD MyasoedovaElena ( View Tweet)
Approaching comorbidities!
Elena Myasoedova @RheumNow #RNL2022 https://t.co/Y3JNsBT9bJ
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
ACPA is a strong predictor for RA development.
any ACPA : 30% developed RA within 3 years.
High titer ACPA: 50% developed RA with 3 years.
Finally ACPA Titer Matters?!
@karen_kc123 @RheumNow #RNL2022 https://t.co/blbVovf1KZ
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
Healthy behaviors (moderate EtOH, healthy body weight, no smoking, healthy diet, physical activity) associated with lower RA risk
"Chronic systemic inflammation fans the flames of brewing RA"
@RheumNow #RNL2022 https://t.co/gAerZaAcso
Robert B Chao, MD doctorRBC ( View Tweet)
Family history risk includes genetic and shared environmental factors
@RheumNow #RNL2022 https://t.co/3J4nisbSX1
Robert B Chao, MD doctorRBC ( View Tweet)
ACPA prior to RA diagnosis.
Notice epitope spreading proceeding diagnosis!!
@karen_kc123 @RheumNow #RNL2022 https://t.co/glgrOdVyyJ
Nouf Al hemmadi NoufAhmedAlham2 ( View Tweet)
Completed Early RA prevention trials using agents like steroids, RTX, atorvastatin, abatacept
No sig difference in steroids, atorvastatin
RTX delayed onset but no overall diff
Abatacept decreased RA progression at 1.5 years
@RheumNow #RNL2022 https://t.co/v7WxI2P7r5
Robert B Chao, MD doctorRBC ( View Tweet)
