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Diagnostic Delay in Axial Spondyloarthritis (2.25.2022)

Jack Cush, MD

Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com. This week, rheumatologic problems incited by respiratory infections, air pollution and how you live, now where you live.

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Low COVID-19 Vaccine Risks in Rheumatic Patients

Jack Cush, MD

Data from the European Alliance of Associations for Rheumatology Coronavirus Vaccine registry shows that patients with with inflammatory or noninflammatory rheumatic and musculoskeletal disease have similar adverse event rates as the general public.

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Increased Odds of Arthritis with Social Risk Factors

Jack Cush, MD

MMWR has published the results of the 2017 Behavioral Risk Factor Surveillance System showing that increases in the number of social risk factors independently increases the odds of arthritis and its burden in the USA.

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RA: Still a Clinical Diagnosis

MedPage Today

Rheumatoid arthritis (RA) is an autoimmune inflammatory disease of the joints, characterized by pain, swelling, and ultimately, if inadequately treated, joint destruction. Despite recent advances in laboratory testing and imaging, the diagnosis of RA remains a clinical one, according to experts.

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RheumNow Podcast - RWCS 2022 Roundup (2.19.2022)

Jack Cush, MD

Drs. Jack Cush and Artie Kavanaugh review the highlights of the RWCS (Rheumatology Winter Clinical Symposium) from Maui.


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BMI Most Impairs Treatment Response in Rheumatoid Arthritis

Jack Cush, MD

Using a large cohort of rheumatoid arthritis (RA) patients, Tumor-Necrosis Factor inhibitors (TNFi) were compared to non-TNFi biologic therapies and showed that poorer responses were seen in obese and underweight patients, with no clear superiority of non-TNFi therapy over TNFi therapy in an

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Rheumatoid Arthritis Nonadherence is Multifactorial

Jack Cush, MD

The consequences of medication non-adherence (NA) in rheumatoid arthritis (RA) care are numerous and damaging.  A 6-month prospective cohort study of RA patients shows NA to vary according to drug type and be related to psychological, communicational, logistic, sociodemographic or clini

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ACR Updates Clinical Guidance for Multisystem Inflammatory Syndrome in Children Associated With COVID

Jack Cush, MD

A Task Force from the ACR has provided an updated (version 3) guidance for the diagnosis and management of Multisystem Inflammatory Syndrome in Children (MIS-C), a COVID related condition characterized by fever, inflammation, and multiorgan dysfunction.

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Vitamin D and the Risk of Autoimmune Diseases

Jack Cush, MD

The results of the VITAL study (presented at ACR 2021) are now published by BMJ, showing that vitamin D and omega 3 fatty acids reduce the overall risk of autoimmune disease (AID) in a population based intervention trial.

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Where you live doesn't alter your risk for RA. Systematic review of 54 articles, 11 studies shows that rural/remote populations had no greater #RA risk. But Rural/remote pts have >barriers to care which increases the risk for inequities in outcomes. https://t.co/8fhFSQ54rt https://t.co/qJhNFcb0b2

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Watch: Treat to Target Strategy in RA: Dr. Dylan Lee at RWCS22 https://t.co/QExalESU2q https://t.co/cqzL4FYOUl

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ICYMI: Voriconazole-induced synovitis, enthesitis and periostitis described in woman treated for invasive aspergillosis. She had polyarthralgias, synovitis, and periostitis on xray. Voriconazole prev. caused periostitis; now drug induced arthritis? https://t.co/6HfLGIaEsU

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NAFLD is increased in #RA. Risk factors include male, BMI, MTX dose, inflammation. @UmaMahadevanIBD @RWCSmtg #rwcs https://t.co/V94aaO5vEH
Dr. John Cush RheumNow ( View Tweet)
Doximity ranked 15 specialties w/ high telehealth adoption rates 1 Endocrinology 2 GI 3. Rheumatology 4 GU 5 Nephrology 6 Cardiology 7 ENT 8 Neuro 9 Allergy 10 Heme/Onc 11Family medicine 12 Dermatology 13 Geriatrics 14 Pulm 15 Psych https://t.co/d7xm1ovk15

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NOR-DRUM study shows that TDM, therapeutic drug monitoring, is beneficial. Study of RA, PSA, AS, Crohn's, UC Rheums don't do this, should they? #RWCS2022 @RWCSmtg https://t.co/Dc6mgr5jrL
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Rheumatoid Arthritis Nonadherence is Multifactorial A 6-month prospective cohort study of RA patients shows NA to vary according to drug type and be related to psychological, communicational, logistic, sociodemographic or clinical factors. https://t.co/FWamPS2fTQ https://t.co/EtoStfdTsI

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Fatigue in Early RA registry - study of n = 1236 pts w/ Dz duration 11 mos. The prevalence rates of fatigue was 44% and severe fatigue 19% and was stable over 3 yrs. Greater fatigue in women, high pain, mental Dz, function; BUT NOT SJC or ESR https://t.co/hEgPbsAqYZ

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CARRA Registry looked at TNFi use in JIA and found a nearly 3 fold increased risk of psoriasis. 8225 pts w/ 3.9 yrs of F/U. 54% recv TNFi; the aHR of new onset of psoriasis after TNFi exposure was 2.93 (2.15 to 3.98). MTX had lower risk (HR 0.45) https://t.co/Z6qvlS26M9

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Analysis of nearly 1000 undifferentiated-arthritis(UA) pts show that MRI use is most effective when applied to those who are seronegative or who have oligoathritis. https://t.co/aKIp2rZSNk

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Prevalence of PsA, axSpA & RA (2017) in Norwegian adults is 0.46%, 0.41%, & 0.78%. In 2017, 27.3% of RA patients, 25.7% of PsA patients and 35.1% of axSpA patients used biologic DMARDs (biologics more freq in youngers; infrequent if ≥55 yrs https://t.co/oqlpPmam6R

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